Recombination, the exchange of DNA between maternal and paternal chromosomes during
meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms …

Selective breeding has been practiced since domestication, but early breeders commonly
selected on appearance (eg, coat color) rather than performance traits (eg, milk yield). A …

Background Major advances in selection progress for cattle have been made following the
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …

Background Inbreeding decreases animal performance (inbreeding depression), but not all
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …

Traditionally, pedigree-based relationship coefficients have been used to manage the
inbreeding and degree of inbreeding depression that exists within a population. The …

Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …

Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …

In the presence of recombination, the evolutionary relationships between a set of sampled
genomes cannot be described by a single genealogical tree. Instead, the genomes are …

Understanding the distribution of crossovers along chromosomes is crucial to evolutionary
genomics because the crossover rate determines how strongly a genome region is …

PRDM9 is a zinc finger protein that binds DNA at specific locations in the genome where it
trimethylates histone H3 at lysines 4 and 36 at surrounding nucleosomes. During meiosis in …