Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

Many studies have provided evidence for the hypothesis that size at birth is related to the
risk of developing disease in later life. In particular, links are well established between …

There is now considerable evidence that elements of the heritable or familial component of
disease susceptibility are transmitted by nongenomic means, and that environmental …

Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …

Developmental programming is the concept that a maternal stimulus or insult at a critical
period in fetal development has long-term effects on the offspring. Historically, considerable …

Abundant evidence supports the association between low birth weight (LBW) and renal
dysfunction in humans. Anatomic measurements of infants, children, and adults show …

The primary markers of the metabolic syndrome are central obesity, insulin resistance and
hypertension. In this review, we consider the effect of changes in maternal nutrition during …

This study utilized maternal undernutrition from early to midgestation in the ewe to determine
the impact (s) of intrauterine growth restriction on postpartum growth of male offspring and …

Knowledge of factors affecting variation in birth weight is especially important given the
relationship of birth weight to neonatal and adult health. The present study utilises two large …

Variation in the quality or quantity of nutrients consumed during pregnancy can exert
permanent and powerful effects upon the developing fetus. This programming of fetal …