Considerable progress has been made in developing models of cerebellar function in
sensorimotor control, as well as in identifying key problems that are the focus of current …

Studies on synaptic plasticity in the context of learning have been dominated by the view
that a single, particular type of plasticity forms the underlying mechanism for a particular type …

Cerebellar granule cells, which constitute half the brain's neurons, supply Purkinje cells with
contextual information necessary for motor learning, but how they encode this information is …

Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …

Although our ability to store semantic declarative information can nowadays be readily
surpassed by that of simple personal computers, our ability to learn and express procedural …

Climbing fiber inputs to Purkinje cells are thought to be involved in generating the instructive
signals that drive cerebellar learning. To investigate how these instructive signals are …

Eyeblink conditioning in restrained rabbits has served as an excellent model of cerebellar-
dependent motor learning for many decades. In mice, the role of the cerebellum in eyeblink …

Closed-loop circuitries between cortical and subcortical regions can facilitate precision of
output patterns, but the role of such networks in the cerebellum remains to be elucidated …

Sensory integration difficulties have been reported in autism, but their underlying brain-
circuit mechanisms are underexplored. Using five autism-related mouse models …

For many decades, the predominant view in the cerebellar field has been that the
olivocerebellar system's primary function is to induce plasticity in the cerebellar cortex …