Function of lipid binding proteins of parasitic helminths: still a long road

JF Lombardo, JL Pórfido, MS Sisti, AN Giorello… - Parasitology …, 2022 - Springer
Infections with parasitic helminths cause severe debilitating and sometimes lethal diseases
in humans and domestic animals on a global scale. Unable to synthesize de novo their own …

Transcriptome profiling of plerocercoid and adult developmental stages of the neglected medical tapeworm Spirometra erinaceieuropaei

SN Liu, XY Su, WQ Chen, JW Yu, JR Li, P Jiang, J Cui… - Acta Tropica, 2022 - Elsevier
The plerocercoid larvae of the tapeworm Spirometra erinaceieuropaei can parasitize
humans and animals and cause serious parasitic zoonosis. However, our knowledge of the …

Cestodes in the genomic era

L Kamenetzky, LL Maldonado, MA Cucher - Parasitology Research, 2022 - Springer
The first cestode genomes were obtained by an international consortium led by the
Wellcome Sanger Institute that included representative institutions from countries where the …

Schistosoma mansoni egg-derived thioredoxin and Sm14 drive the development of IL-10 producing regulatory B cells

MAM Chayé, TA Gasan… - PLoS neglected …, 2023 - journals.plos.org
During chronic schistosome infections, a complex regulatory network is induced to regulate
the host immune system, in which IL-10-producing regulatory B (Breg) cells play a significant …

Application of target repositioning and in silico screening to exploit fatty acid binding proteins (FABPs) from Echinococcus multilocularis as possible drug targets

JA Bélgamo, LN Alberca, JL Pórfido… - Journal of Computer …, 2020 - Springer
Fatty acid binding proteins (FABPs) are small intracellular proteins that reversibly bind fatty
acids and other hydrophobic ligands. In cestodes, due to their inability to synthesise fatty …

Molecular Characteristics of the Fatty-Acid-Binding Protein (FABP) Family in Spirometra mansoni―A Neglected Medical Tapeworm

S Liu, F Gao, R Wang, W Li, S Wang, X Zhang - Animals, 2023 - mdpi.com
Simple Summary The purpose of this study was to investigate the members, gene
expression patterns, and molecular characteristics of the Spirometra mansoni fatty-acid …

Molecular characteristics of Echinococcus multilocularis FABP1 and its regulatory functions on murine macrophages

X Li, P Liao, W Zhou, X Yang, B Ye - Acta Tropica, 2024 - Elsevier
Fatty acid binding proteins (FABPs) have emerged as attractive vaccination candidates for
several platyhelminth species. To explore the physiological functions of Echinococcus …

Echinococcus: the model cestode parasite

A Hemphill, B Lundström-Stadelmann - Parasitology, 2021 - cambridge.org
Cestodes are important endoparasitic organisms, some of which are responsible for serious
zoonotic diseases. The most severe diseases are inflicted by the larval stages …

Transcriptomic Analysis of the Early Strobilar Development of Echinococcus granulosus

JA Debarba, MPC Sehabiague, KM Monteiro… - Pathogens, 2020 - mdpi.com
Echinococcus granulosus has a complex life cycle involving two mammalian hosts. The
transition from one host to another is accompanied by changes in gene expression, and the …

Transcriptional effects of electroporation on Echinococcus multilocularis primary cell culture

MG Pérez, N Rego, M Spiliotis, K Brehm… - Parasitology …, 2022 - Springer
Echinococcus multilocularis is the etiological agent of alveolar echinococcosis (AE), a
serious parasitic disease in the Northern Hemisphere. The E. multilocularis primary cell …