The antibacterial agents currently in clinical development are predominantly derivatives of
well-established antibiotic classes and were selected to address the class-specific …

Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

Molecular and genomic surveillance systems for bacterial pathogens currently rely on
tracking clonally evolving lineages. By contrast, plasmids are usually excluded or analyzed …

New Delhi metallo-β-lactamase (NDM) carbapenemase has been considered a global
threat due to its worldwide widespread in recent years. In Portugal, a very low number of …

Infections with antibiotic resistant pathogens threaten lives and cause substantial costs. For
effective interventions, knowledge of the transmission paths of resistant bacteria to humans …

The chicken gut microbiota, as a reservoir of antibiotic resistance genes (ARGs), poses a
high risk to humans and animals worldwide. Yet a comprehensive exploration of the chicken …

Objectives CARB-ES-19 is a comprehensive, multicenter, nationwide study integrating
whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K …

Objectives To describe and analyse erythromycin resistance trends in blood isolates of
Staphylococcus aureus (EARS-Net Spain, 2004–2020) and the association of these trends …

Abstract Background Carbapenem-resistant Enterobacterales (CRE) harboring blaKPC
have been endemic in Chicago-area healthcare networks for more than a decade. During …

The emergence of 16S rRNA methyltransferases (RMTs) in Gram-negative pathogens
bearing other clinically relevant resistance mechanisms, such as carbapenemase-producing …