There is a huge potential market for the treatment of hearing loss. Drugs are already
available to ameliorate predictable, damaging effects of excessive noise and ototoxic drugs …

Cochlear ganglion neurons communicate sound information from cochlear hair cells to
auditory brainstem neurons through precisely wired circuits. Understanding auditory circuit …

The POU-domain transcription POU4F3 is expressed in the sensory cells of the inner ear.
Expression begins shortly after commitment to the hair cell (HC) fate, and continues …

We have developed a technique to deliver cells to the inner ear without injuring the
membranes that seal the endolymphatic and perilymphatic chambers. The integrity of these …

Hearing loss is among the most prevalent sensory impairments in humans. Cochlear
implantable devices represent the current therapies for hearing loss but have various …

Hearing loss affects millions of people in the world. In mammals the auditory system
comprises diverse cell types which are terminally differentiated and with no regenerative …

OBJECTIVE: The peripheral auditory nervous system (cochlea and auditory nerve) has a
complex anatomy, and it has traditionally been thought that once the sensorineural …

Auditory neurons connect the sensory hair cells from the inner ear to the brainstem. These
bipolar neurons are relevant targets for pharmacological intervention aiming at protecting or …

Meis genes have been shown to control essential processes during development of the
central and peripheral nervous system. Here we have explored the roles of the Meis2 gene …

The histone demethylase LSD1 plays a pivotal role in cellular differentiation, particularly in
silencing lineage-specific genes. However, little is known about how LSD1 regulates …