Context Continuing advances in genotyping technologies and the inclusion of DNA
collection in observational studies have resulted in an increasing number of genetic …

Genetic variation in DNA repair genes can modulate DNA repair capacity and may be
related to cancer risk. However, study findings have been inconsistent. Inheritance of variant …

Lung cancer is one of the most common and deadliest cancers in the world. The major socio-
environmental risk factor involved in the development of lung cancer is cigarette smoking …

Base excision repair (BER) is the primary DNA damage repair mechanism for repairing
small base lesions resulting from oxidation and alkylation damage. This study examines the …

Genetic variations in DNA repair genes are thought to modulate DNA repair capacity and
are suggested to be related to lung cancer risk. We conducted a meta‐analysis of …

Effective DNA repair machinery ensures maintenance of genomic integrity. Environmental
insults, ageing and replication errors necessitate the need for proper DNA repair systems …

Advanced stage non-small cell lung cancer and head and neck squamous cell carcinoma
are both treated with DNA damaging agents including platinum-based compounds and …

Background The prevalence of lung cancer in China will be the world's highest if allowed to
proceed uncurbed. To unravel its genetic underpinnings, we sought to investigate the …

DNA repair plays a critical role in protecting the genome of the cell from the insults of
carcinogens or ionizing radiation. Reduced DNA repair capacity can increase the …

Genetic variations in DNA repair genes are thought to modify DNA repair capacity and
suggested to be related to cancer risk. However, epidemiological results have been …