Mechanical properties of whole-body soft human tissues: a review

G Singh, A Chanda - Biomedical Materials, 2021 - iopscience.iop.org
The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Multifaceted design and emerging applications of tissue adhesives

Z Ma, G Bao, J Li - Advanced Materials, 2021 - Wiley Online Library
Tissue adhesives can form appreciable adhesion with tissues and have found clinical use in
a variety of medical settings such as wound closure, surgical sealants, regenerative …

Reversed-engineered human alveolar lung-on-a-chip model

D Huang, T Liu, J Liao, S Maharjan… - Proceedings of the …, 2021 - National Acad Sciences
Here, we present a physiologically relevant model of the human pulmonary alveoli. This
alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made …

3D printed deformable sensors

Z Zhu, HS Park, MC McAlpine - Science advances, 2020 - science.org
The ability to directly print compliant biomedical devices on live human organs could benefit
patient monitoring and wound treatment, which requires the 3D printer to adapt to the …

[HTML][HTML] Techniques for characterizing mechanical properties of soft tissues

K Navindaran, JS Kang, K Moon - Journal of the Mechanical Behavior of …, 2023 - Elsevier
The characterization of soft tissues remains a vital need for various bioengineering and
medical fields. Developing areas such as regenerative medicine, robot-aided surgery, and …

Advances in 3D bioprinting for cancer biology and precision medicine: From matrix design to application

MS Jung, S Ghamrawi, EY Du… - Advanced …, 2022 - Wiley Online Library
The tumor microenvironment is highly complex owing to its heterogeneous composition and
dynamic nature. This makes tumors difficult to replicate using traditional 2D cell culture …

Cavitation in soft matter

CW Barney, CE Dougan, KR McLeod… - Proceedings of the …, 2020 - National Acad Sciences
Cavitation is the sudden, unstable expansion of a void or bubble within a liquid or solid
subjected to a negative hydrostatic stress. Cavitation rheology is a field emerging from the …

A review of biomaterials and scaffold fabrication for organ-on-a-chip (OOAC) systems

LA Osório, E Silva, RE Mackay - Bioengineering, 2021 - mdpi.com
Drug and chemical development along with safety tests rely on the use of numerous clinical
models. This is a lengthy process where animal testing is used as a standard for pre-clinical …

[HTML][HTML] An in vitro model of fibrosis using crosslinked native extracellular matrix-derived hydrogels to modulate biomechanics without changing composition

M Nizamoglu, RHJ de Hilster, F Zhao, PK Sharma… - Acta biomaterialia, 2022 - Elsevier
Extracellular matrix (ECM) is a dynamic network of proteins, proteoglycans and
glycosaminoglycans, providing structure to the tissue and biochemical and biomechanical …

Real‐Time Measurement of Cell Mechanics as a Clinically Relevant Readout of an In Vitro Lung Fibrosis Model Established on a Bioinspired Basement Membrane

A Doryab, MB Taskin, P Stahlhut, J Groll… - Advanced …, 2022 - Wiley Online Library
Lung fibrosis, one of the major post‐COVID complications, is a progressive and ultimately
fatal disease without a cure. Here, an organ‐and disease‐specific in vitro mini‐lung fibrosis …