Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

Bacteriophages for the targeted control of foodborne pathogens

EW Bumunang, R Zaheer, D Niu, C Narvaez-Bravo… - Foods, 2023 - mdpi.com
Foodborne illness is exacerbated by novel and emerging pathotypes, persistent
contamination, antimicrobial resistance, an ever-changing environment, and the complexity …

Phage biobank: present challenges and future perspectives

RCY Lin, JC Sacher, PJ Ceyssens, J Zheng… - Current opinion in …, 2021 - Elsevier
After a century of use in human infection, the preparation and administration of therapeutic
bacteriophages (phages) still relies on ad hoc partnerships of researchers, biotech …

Phage therapy in the 21st century: is there modern, clinical evidence of phage-mediated efficacy?

ST Abedon, KM Danis-Wlodarczyk, DR Alves - Pharmaceuticals, 2021 - mdpi.com
Many bacteriophages are obligate killers of bacteria. That this property could be medically
useful was first recognized over one hundred years ago, with 2021 being the 100-year …

Phage therapy: an alternative treatment modality for MDR bacterial infections

N Pal, P Sharma, M Kumawat, S Singh… - Infectious …, 2024 - Taylor & Francis
The increasing global incidence of multidrug-resistant (MDR) bacterial infections threatens
public health and compromises various aspects of modern medicine. Recognising the …

Alternative treatment strategies for secondary bacterial and fungal infections associated with COVID-19

R Das, K Kotra, P Singh, B Loh, S Leptihn… - Infectious diseases and …, 2022 - Springer
Antimicrobials are essential for combating infectious diseases. However, an increase in
resistance to them is a major cause of concern. The empirical use of drugs in managing …

Freeze-drying of encapsulated bacteriophage T4 to Obtain Shelf-stable dry preparations for oral application

P Śliwka, G Skaradziński, I Dusza, A Grzywacz… - Pharmaceutics, 2023 - mdpi.com
Therapeutic application of bacterial viruses (phage therapy) has in recent years been
rediscovered by many scientists, as a method which may potentially replace conventional …

Decoding the molecular properties of mycobacteriophage D29 holin provides insights into holin engineering

VR Bavda, A Yadav, V Jain - Journal of Virology, 2021 - Am Soc Microbiol
Holins are bacteriophage-encoded small transmembrane proteins that determine the phage
infection cycle duration by forming nonspecific holes in the host cell membrane at a specific …

[PDF][PDF] Harnessing Bacteriophages to Combat Antibiotic-Resistant Infections in Africa: A Comprehensive Review. Antibiotics 2024, 13, 795. htps

K Fabiyi, K Sintondji, J Agbankpe… - doi. org/10.3390 …, 2024 - researchgate.net
The conventional treatment of bacterial infections with antibiotics is becoming increasingly
ineffective due to the emergence of multidrug-resistant (MDR) pathogens. This literature …

Phage Therapy: A Clinician's Guide

KM Danis-Wlodarczyk, DR Alves… - Handbook of Molecular … - taylorfrancis.com
Bacteriophages, or phages, are the viruses of bacteria. Known to science for over 100 years,
the use of phages as antibacterial agents predates the discovery and substantial clinical …