Broad spectrum antiviral agent niclosamide and its therapeutic potential
The recent outbreak of coronavirus disease 2019 (COVID-19) highlights an urgent need for
therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an …
therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an …
Application of mesoporous silica nanoparticles in cancer therapy and delivery of repurposed anthelmintics for cancer therapy
This review focuses on the biomedical application of mesoporous silica nanoparticles
(MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and …
(MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and …
Drug repurposing for cancer therapy
Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …
health. Despite significant advances in surgical, radiotherapeutic and immunological …
Comprehensive review on current interventions, diagnostics, and nanotechnology perspectives against SARS-CoV-2
The coronavirus disease 2019 (COVID-19) has dramatically challenged the healthcare
system of almost all countries. The authorities are struggling to minimize the mortality along …
system of almost all countries. The authorities are struggling to minimize the mortality along …
Repurposing old drugs to fight multidrug resistant cancers
Overcoming multidrug resistance represents a major challenge for cancer treatment. In the
search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a …
search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a …
Quality by design steered development of Niclosamide loaded liposomal thermogel for Melanoma: In vitro and Ex vivo evaluation
Melanoma is the most malignant form of skin cancer across the globe. Conventional
therapies are currently ineffective which could be attributed to the rampant chemo …
therapies are currently ineffective which could be attributed to the rampant chemo …
Direct cyclodextrin-based powder extrusion 3D printing for one-step production of the BCS class II model drug niclosamide
M Pistone, GF Racaniello, I Arduino… - Drug Delivery and …, 2022 - Springer
Niclosamide (NCS) is a drug that has been used as an anthelmintic and anti-parasitic drug
for about 40 years. Recently, some studies have highlighted its potential in treating various …
for about 40 years. Recently, some studies have highlighted its potential in treating various …
Niclosamide inhalation powder made by thin-film freezing: Multi-dose tolerability and exposure in rats and pharmacokinetics in hamsters
In this work, we have developed and tested a dry powder form of niclosamide made by thin-
film freezing (TFF) and administered it by inhalation to rats and hamsters to gather data …
film freezing (TFF) and administered it by inhalation to rats and hamsters to gather data …
[HTML][HTML] Anthelmintics for drug repurposing: Opportunities and challenges
SE Alavi, HE Shahmabadi - Saudi Pharmaceutical Journal, 2021 - Elsevier
Drug repositioning is defined as a process to identify a new application for drugs. This
approach is critical as it takes advantage of well-known pharmacokinetics …
approach is critical as it takes advantage of well-known pharmacokinetics …
Drug repurposing in rare diseases: Myths and reality
C Fetro, D Scherman - Therapies, 2020 - Elsevier
While nearly 8000 rare diseases have been identified, only 5 percent have licensed
treatments. As most of these diseases are life threatening, it underscores the urgent need for …
treatments. As most of these diseases are life threatening, it underscores the urgent need for …