Wettability-patterned microchip for emerging biomedical materials and technologies
Microchip has long been studied and facilitated recent investigations in multiple biomedical
and material fields. The advances in functional materials triggered several leaps in the …
and material fields. The advances in functional materials triggered several leaps in the …
Understanding Molecular Transfer between Aqueous Phase and Reverse Micelles and Its Application to Bioassays in Microfluidics
M Fukuyama - Bulletin of the Chemical Society of Japan, 2023 - academic.oup.com
Micrometer-sized water-in-oil droplets (microdroplets) are attracting attention as carriers for
the high-throughput parallel analysis of trace samples. By confining trace amounts of water …
the high-throughput parallel analysis of trace samples. By confining trace amounts of water …
Nanoparticle Assembly at the Water–Oil Interface Induced by Spontaneous Emulsification for Microdroplet Immunoassay
M Fukuyama, K Kubota, A Hibara - Langmuir, 2023 - ACS Publications
Micron-sized water-in-oil droplets (microdroplets) have been used for various biochemical
analyses. Many studies have been reported on immunoassays using microdroplets because …
analyses. Many studies have been reported on immunoassays using microdroplets because …
Resistive Pulse Sensing on a Capillary-Assisted Microfluidic Platform for On-Site Single-Particle Analyses
T Shimada, K Fujino, T Yasui, N Kaji, Y Ueda… - Analytical …, 2023 - ACS Publications
Capillary-assisted flow is valuable for utilizing microfluidics-based electrical sensing
platforms at on-site locations by simplifying microfluidic operations and system construction; …
platforms at on-site locations by simplifying microfluidic operations and system construction; …
Monodisperse liposomes with femtoliter volume enable quantitative digital bioassays of membrane transporters and cell-free gene expression
N Soga, A Ota, K Nakajima, R Watanabe, H Ueno… - ACS …, 2020 - ACS Publications
Digital bioassays have emerged as a new category of bioanalysis. However, digital
bioassays for membrane transporter proteins have not been well established yet despite …
bioassays for membrane transporter proteins have not been well established yet despite …
High-throughput single-molecule bioassay using micro-reactor arrays with a concentration gradient of target molecules
Micro-reactor arrays enable highly sensitive and quantitative bioassays at a single-molecule
level. Accordingly, they are widely used for sensitive “digital” bioassays, eg, digital PCR and …
level. Accordingly, they are widely used for sensitive “digital” bioassays, eg, digital PCR and …
Sensitivity-improved blocking agent-free fluorescence polarization assay through surface modification using polyethylene glycol
H Liu, M Fukuyama, Y Ogura, M Kasuya, S Onose… - Analyst, 2024 - pubs.rsc.org
Fluorescence polarization (FP) assays are widely used to quantify biomolecules, and their
combination with microfluidic devices has the potential for application in onsite analysis …
combination with microfluidic devices has the potential for application in onsite analysis …
Controlling water transport between micelles and aqueous microdroplets during sample enrichment
M Fukuyama, L Zhou, T Okada, KV Simonova… - Analytica Chimica …, 2021 - Elsevier
Droplet microfluidics technologies have advanced rapidly, but enrichment in droplets has
still been difficult. To deterministically control the droplet enrichment, the water transport from …
still been difficult. To deterministically control the droplet enrichment, the water transport from …
Light fueled mixing in open surface droplet microfluidics for rapid probe preparation
In this study, a contactless, flexible, and interference-free light fueled method has been
developed to enhance the mixing between the ssDNA and dynabeads in a droplet, which …
developed to enhance the mixing between the ssDNA and dynabeads in a droplet, which …
Transport of Oligopeptide from Aqueous Phase to Span 80 Reverse Micelles in Microdroplet Array
M Fukuyama, M Suto, A Hibara - Analytical Sciences, 2021 - Springer
The partitioning of water and tetramethylrhodamine-conjugated-10-residue oligopeptides
from the aqueous phase of microdroplets into Span 80 reverse micelles was observed by …
from the aqueous phase of microdroplets into Span 80 reverse micelles was observed by …