We are currently witnessing transformative change for people with cystic fibrosis with the
introduction of small molecule, mutation-specific drugs capable of restoring function of the …

Some cannabinoids activate the different isoforms of PPARs (α, β and γ), as shown through
the use of reporter gene assays, binding studies, selective antagonists and knockout …

Cannabinoids are a group of compounds that mediate their effects through cannabinoid
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …

Cannabinoids can influence the immune network. Data on the impact of exogenous
cannabinoid ligands on immune function serve not only to understand how the …

Objective To assess the safety and efficacy of lenabasum in diffuse cutaneous systemic
sclerosis (dc SS c). Methods A randomized, double‐blind, placebo‐controlled, phase II study …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

This review covers reports published in the last 5 years on the anti-inflammatory activities of
all classes of cannabinoids, including phytocannabinoids such as tetrahydrocannabinol and …

Cannabinoids apparently act on inflammation through mechanisms different fromthose of
agents such as nonsteroidal anti‐inflammatory drugs (NSAIDs). As a class, the …

Background Treatment options are limited for skin disease in dermatomyositis. Lenabasum
is a cannabinoid receptor type 2 agonist that triggers the resolution of inflammation …

Since the discovery of the endocannabinoid system consisting of cannabinoid receptors,
endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been …