Neisseria meningitidis is a gram-negative diplococcus and a transient commensal of the
human nasopharynx. It shares and competes for this niche with a number of other Neisseria …

Glycomics is a rapidly growing field that focuses on the structure and function of
carbohydrates (glycans) in biological systems. Glycan interactions play a major role in …

Workflows capable of determining glycopeptides in large-scale are missing in the field of
glycoproteomics. We present an approach for automated annotation of intact glycopeptide …

Neisseria gonorrhoeae is an obligate human pathogen that is the cause of the sexually
transmitted disease gonorrhoea. Recently, there has been a surge in gonorrhoea cases that …

Neisseria meningitidis exhibits a general O-linked protein glycosylation system in which pili
and other extracytoplasmic proteins are glycosylated. To investigate glycan antigenicity in …

Sialylation of lacto-N-neotetraose (LNnT) extending from heptose I (HepI) of gonococcal
lipooligosaccharide (LOS) contributes to pathogenesis. Previously, gonococcal LOS …

In the meningitis belt of sub-Saharan Africa, there are cyclic meningococcal epidemics that
coincide with clonal waves of Neisseria meningitidis carriage and invasive disease. In the …

Type IV pili (Tfp) are functionally versatile filaments, widespread in prokaryotes, that belong
to a large class of filamentous nanomachines known as type IV filaments (Tff). Although Tfp …

Increasing evidence demonstrates that lysine acetylation is involved in Mycobacterium
tuberculosis (Mtb) virulence and pathogenesis. However, previous investigations in Mtb …

N-Acetyl modification, a chemical modification commonly found on biomacromolecules,
plays a crucial role in the regulation of cell activities and is related to a variety of diseases …