It has been nearly half a century since angioimmunoblastic T-cell lymphoma (AITL) was
characterized in the early 1970's. Our understanding of the disease has dramatically …

With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Peripheral T-cell lymphoma, not otherwise specified, is a broad category of biologically and
clinically heterogeneous diseases that cannot be further classified into any other of the …

Anaplastic large cell lymphomas (ALCLs) are CD30-positive T-cell non-Hodgkin lymphomas
broadly segregated into ALK-positive and ALK-negative types. Although ALK-positive …

Peripheral T-cell lymphomas (PTCLs) represent a group of rare hematological cancers of
mature T-cell or natural killer cell origin accounting for 10% to 15% of all lymphomas. 1 …

Introduction Malignant pleural mesothelioma is a disease primarily associated with
exposure to the carcinogen asbestos. Whereas other carcinogen-related tumors are …

Anaplastic large cell lymphomas (ALCLs) represent a group of CD30-positive T-cell non-
Hodgkin lymphomas with unifying morphological characteristics but variable clinical and …

Abstract Somatic G17V RHOA mutations were found in 50–70% of angioimmunoblastic T-
cell lymphoma (AITL). The mutant RHOA lacks GTP binding capacity, suggesting defects in …

Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of non-Hodgkin
lymphomas frequently associated with poor prognosis and for which genetic mechanisms of …

To improve our understanding of ovarian cancer, we performed genome-wide analyses of
45 ovarian cancer cell lines. Given the challenges of genomic analyses of tumors without …