Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
Applications of ruthenium complex in tumor diagnosis and therapy
K Lin, ZZ Zhao, HB Bo, XJ Hao, JQ Wang - Frontiers in Pharmacology, 2018 - frontiersin.org
Ruthenium complexes are a new generation of metal antitumor drugs that are currently of
great interest in multidisciplinary research. In this review article, we introduce the …
great interest in multidisciplinary research. In this review article, we introduce the …
Recent studies on the antimicrobial activity of transition metal complexes of groups 6–12
S Nasiri Sovari, F Zobi - Chemistry, 2020 - mdpi.com
Antimicrobial resistance is an increasingly serious threat to global public health that requires
innovative solutions to counteract new resistance mechanisms emerging and spreading …
innovative solutions to counteract new resistance mechanisms emerging and spreading …
Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review
AC Munteanu, V Uivarosi - Pharmaceutics, 2021 - mdpi.com
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …
populations of microorganisms. Clearly, one can see the need to develop new, more …
Role of carbon monoxide in host–gut microbiome communication
CP Hopper, LK De La Cruz, KV Lyles… - Chemical …, 2020 - ACS Publications
Nature is full of examples of symbiotic relationships. The critical symbiotic relation between
host and mutualistic bacteria is attracting increasing attention to the degree that the gut …
host and mutualistic bacteria is attracting increasing attention to the degree that the gut …
[HTML][HTML] Biological properties of ruthenium (II)/(III) complexes with flavonoids as ligands
This review highlights the progress in the development of ruthenium (II)/(III) complexes with
flavone derivatives as potential therapeutic agents. We focused on natural hydroxyflavone …
flavone derivatives as potential therapeutic agents. We focused on natural hydroxyflavone …
[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3
HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects
HM Southam, MP Williamson, JA Chapman, RL Lyon… - Antioxidants, 2021 - mdpi.com
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
The elements of life: A biocentric tour of the periodic table
KA Remick, JD Helmann - Advances in microbial physiology, 2023 - Elsevier
Living systems are built from a small subset of the atomic elements, including the bulk
macronutrients (C, H, N, O, P, S) and ions (Mg, K, Na, Ca) together with a small but variable …
macronutrients (C, H, N, O, P, S) and ions (Mg, K, Na, Ca) together with a small but variable …
Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance
In the last century, conventional antibiotics have played a significant role in global
healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously …
healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously …