Dietary flavonoids: Cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns

J Khan, PK Deb, S Priya, KD Medina, R Devi… - Molecules, 2021 - mdpi.com
Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …

The protective effects of rutin on the liver, kidneys, and heart by counteracting organ toxicity caused by synthetic and natural compounds

S Rahmani, K Naraki, A Roohbakhsh… - Food science & …, 2023 - Wiley Online Library
Rutin is a flavonoid present in many plant species. Because of its antioxidant, anti‐
inflammatory, and antiapoptotic properties, rutin is of interest for its potential protective …

Natural products for the prevention and control of the COVID-19 pandemic: sustainable bioresources

RK Singla, X He, H Chopra, C Tsagkaris… - Frontiers in …, 2021 - frontiersin.org
Background: The world has been unprecedentedly hit by a global pandemic which broke the
record of deadly pandemics that faced humanity ever since its existence. Even kids are well …

A study on the effect of natural products against the transmission of B. 1.1. 529 Omicron

SS Alkafaas, AM Abdallah, AM Hussien, H Bedair… - Virology Journal, 2023 - Springer
Background The recent outbreak of the Coronavirus pandemic resulted in a successful
vaccination program launched by the World Health Organization. However, a large …

Rutin prevents inflammation induced by lipopolysaccharide in RAW 264.7 cells via conquering the TLR4-MyD88-TRAF6-NF-κB signalling pathway

C Tian, X Liu, Y Chang, R Wang… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Inflammation widely exists in many diseases and poses a great threat to human
and animal health. Rutin, quercetin-3-rhamnosyl glucoside, has a variety of pharmacological …

Qiliqiangxin attenuates oxidative stress-induced mitochondrion-dependent apoptosis in cardiomyocytes via PI3K/AKT/GSK3β signaling pathway

Q Zhao, H Li, L Chang, C Wei, Y Yin, H Bei… - Biological and …, 2019 - jstage.jst.go.jp
Qiliqiangxin capsule (QLQX) is a well-known traditional Chinese medicine that exhibits
cardioprotective effects in heart failure patients. However, it remains unclear whether and by …

Qualitative and quantitative analysis of the chemical profile for Gualou-Xiebai-Banxia decoction, a classical traditional Chinese medicine formula for the treatment of …

P Lin, Q Wang, Y Liu, H Jiang, W Lv, T Lan… - … of pharmaceutical and …, 2021 - Elsevier
Abstract Gualou-Xiebai-Banxia decoction (GXB) is one of the famous classical traditional
Chinese Medicine (TCM) formula for the treatment of chest stuffiness and pains syndrome in …

3-Hydroxyflavone is a mildly active and safe cobalt chelator while cobalt markedly enhances baicalein toxicity toward erythrocytes

M Moravcová, Z Lomozová, R Kučera, P Mladěnka - RSC advances, 2023 - pubs.rsc.org
Cobalt intoxication can occur after its release from metal-based prostheses, which is
generally clinically severe. Therefore, there is a need for the development of a cobalt …

Rutin alleviates cardiomyocyte injury induced by high glucose through inhibiting apoptosis and endoplasmic reticulum stress

J Wang, R Wang, J Li, Z Yao - Experimental and …, 2021 - spandidos-publications.com
Diabetic cardiomyopathy is a common complication of diabetes, in which endoplasmic
reticulum stress (ERS) serves an important role. Rutin can treat the myocardial dysfunction …

Norwogonin attenuates hypoxia-induced oxidative stress and apoptosis in PC12 cells

L Jing, R Gao, J Zhang, D Zhang, J Shao, Z Jia… - … Medicine and Therapies, 2021 - Springer
Background Norwogonin is a natural flavone with three phenolic hydroxyl groups in skeletal
structure and has excellent antioxidant activity. However, the neuroprotective effect of …