Diversity and evolution of the animal virome

E Harvey, EC Holmes - Nature Reviews Microbiology, 2022 - nature.com
The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

The ecology of viral emergence

EC Holmes - Annual Review of Virology, 2022 - annualreviews.org
The coronavirus disease 2019 (COVID-19) pandemic has had a profound impact on human
health, economic well-being, and societal function. It is essential that we use this …

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

W Barrie, Y Yang, EK Irving-Pease, KE Attfield… - Nature, 2024 - nature.com
Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …

Archival influenza virus genomes from Europe reveal genomic variability during the 1918 pandemic

LV Patrono, B Vrancken, M Budt, A Düx… - Nature …, 2022 - nature.com
The 1918 influenza pandemic was the deadliest respiratory pandemic of the 20th century
and determined the genomic make-up of subsequent human influenza A viruses (IAV). Here …

Transboundary animal diseases, an overview of 17 diseases with potential for global spread and serious consequences

EA Clemmons, KJ Alfson, JW Dutton III - Animals, 2021 - mdpi.com
Simple Summary Animals provide food and other critical resources to much of the global
population. Transboundary animal diseases are highly contagious or transmissible …

Virology—The next fifty years

EC Holmes, F Krammer, FD Goodrum - Cell, 2024 - cell.com
Virology has made enormous advances in the last 50 years but has never faced such
scrutiny as it does today. Herein, we outline some of the major advances made in virology …

[HTML][HTML] Ancient bacterial genomes reveal a high diversity of Treponema pallidum strains in early modern Europe

K Majander, S Pfrengle, A Kocher, J Neukamm… - Current Biology, 2020 - cell.com
Syphilis is a globally re-emerging disease, which has marked European history with a
devastating epidemic at the end of the 15 th century. Together with non-venereal treponemal …

The recovery, interpretation and use of ancient pathogen genomes

S Duchêne, SYW Ho, AG Carmichael, EC Holmes… - Current Biology, 2020 - cell.com
The ability to sequence genomes from ancient biological material has provided a rich source
of information for evolutionary biology and engaged considerable public interest. Although …

Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade

AA Guzmán-Solís, V Villa-Islas, MJ Bravo-López… - Elife, 2021 - elifesciences.org
After the European colonization of the Americas, there was a dramatic population collapse of
the Indigenous inhabitants caused in part by the introduction of new pathogens. Although …

A mechanistic evolutionary model explains the time-dependent pattern of substitution rates in viruses

M Ghafari, P Simmonds, OG Pybus, A Katzourakis - Current Biology, 2021 - cell.com
Estimating viral timescales is fundamental in understanding the evolutionary biology of
viruses. Molecular clocks are widely used to reveal the recent evolutionary histories of …