Therapeutic progress and challenges for triple negative breast cancer: Targeted therapy and immunotherapy

R Yang, Y Li, H Wang, T Qin, X Yin, X Ma - Molecular biomedicine, 2022 - Springer
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

Updating the clinical application of blood biomarkers and their algorithms in the diagnosis and surveillance of hepatocellular carcinoma: a critical review

E Shahini, G Pasculli, AG Solimando, C Tiribelli… - International Journal of …, 2023 - mdpi.com
The most common primary liver cancer is hepatocellular carcinoma (HCC), and its mortality
rate is increasing globally. The overall 5-year survival of patients with liver cancer is …

[HTML][HTML] Research progress in nano-drug delivery systems based on the characteristics of the liver cancer microenvironment

S Lu, C Zhang, J Wang, L Zhao, G Li - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The liver cancer has microenvironmental features such as low pH, M2 tumor-associated
macrophage enrichment, low oxygen, rich blood supply and susceptibility to hematotropic …

WNK1–OSR1 Signaling Regulates Angiogenesis-Mediated Metastasis towards Developing a Combinatorial Anti-Cancer Strategy

CY Hou, CY Ma, YJ Lin, CL Huang, HD Wang… - International journal of …, 2022 - mdpi.com
Lysine-deficient protein kinase-1 (WNK1) is critical for both embryonic angiogenesis and
tumor-induced angiogenesis. However, the downstream effectors of WNK1 during these …

Differential in vitro effects of targeted therapeutics in primary human liver cancer: importance for combined liver cancer

IA Malik, M Rajput, R Werner, D Fey, N Salehzadeh… - BMC cancer, 2022 - Springer
The incidence of primary liver tumors, hepatocellular carcinoma (HCC), intrahepatic
cholangiocellular carcinoma (ICC), and combined HCC/ICC (cHCC/CC) is increasing. For …

Efficacy and safety of HAIC alone vs. HAIC combined with lenvatinib for treatment of advanced hepatocellular carcinoma

F Long, S Chen, R Li, Y Lin, J Han, J Guo, Y Chen… - Medical Oncology, 2023 - Springer
To investigate efficacy and safety of hepatic arterial infusion chemotherapy combined with
lenvatinib (HAIC-Len) and HAIC alone for the treatment of advanced hepatocellular …

Lenvatinib plus transarterial chemoembolization with or without immune checkpoint inhibitors for unresectable hepatocellular carcinoma: A review

L Sun, X Xu, F Meng, Q Liu, H Wang, X Li, G Li… - Frontiers in …, 2022 - frontiersin.org
Lenvatinib plus transarterial chemoembolization (TACE) have become the first choice for
patients with hepatocellular carcinoma (HCC) that are unsuitable for TACE. Sorafenib plus …

Downstaging Techniques for Hepatocellular Carcinoma in Candidates Awaiting Liver Transplantation

L Matevish, MS Patel, PA Vagefi - Surgical Clinics, 2024 - surgical.theclinics.com
Primary liver cancer is the sixth most common cause of cancer deaths in the United States
with hepatocellular carcinoma (HCC) representing approximately 75% of cases. 1 The most …

Baseline Albumin-Bilirubin grade as a predictor of response and outcome of regorafenib therapy in patients with hepatocellular carcinoma: a systematic review and …

H Xu, D Cao, D Zhou, N Zhao, X Tang, VG Shelat… - BMC cancer, 2023 - Springer
Background The use of regorafenib in the treatment of hepatocellular carcinoma (HCC) is
widespread. Albumin-Bilirubin (ALBI) has been shown to be a potential prognostic marker …

[HTML][HTML] Microwave ablation as a primary versus secondary treatment for hepatocellular carcinoma

P Lee, A Makkena, M Tantawi… - Diagnostic and …, 2023 - ncbi.nlm.nih.gov
PURPOSE The purpose of this study was to analyze and compare the outcomes of
percutaneous microwave ablation (MWA) when used as a primary vs. secondary treatment …