Phenytoin–An anti-seizure drug: Overview of its chemistry, pharmacology and toxicology

J Patocka, Q Wu, E Nepovimova, K Kuca - Food and Chemical Toxicology, 2020 - Elsevier
Phenytoin is a long-standing, anti-seizure drug widely used in clinical practice. It has also
been evaluated in the context of many other illnesses in addition to its original epilepsy …

Dual-drug delivery of Ag-chitosan nanoparticles and phenytoin via core-shell PVA/PCL electrospun nanofibers

MAM Hussein, E Guler, E Rayaman, ME Cam… - Carbohydrate …, 2021 - Elsevier
Dual-drug delivery systems were constructed through coaxial techniques, which were
convenient for the model drugs used the present work. This study aimed to fabricate core …

[HTML][HTML] CCN2: a potential contributor to gingival overgrowth

A Fadl, A Leask - Journal of Oral Biosciences, 2024 - Elsevier
Background Fibrotic responses in the gingiva are characterized by their hyperproliferative
nature instead of scar tissue formation. Clinically, these conditions appear as “gingival …

Gingival overgrowth induced by anticonvulsant drugs: A cross‐sectional study on epileptic patients

C Gallo, G Bonvento, G Zagotto… - Journal of …, 2021 - Wiley Online Library
Objective Our aim was to estimate the prevalence of gingival overgrowth (hyperplasia) and
to determine whether active molecules affect the severity of overgrowth in a group of …

Novel microfluidic development of pH-responsive hybrid liposomes: In vitro and in vivo assessment for enhanced wound Healing

H Alaqabani, A Hammad, Y Abosnwber… - International Journal of …, 2024 - Elsevier
Wound healing is a complex biological process crucial for tissue repair, especially in chronic
wounds where healing is impaired. Liposomes have emerged as promising vehicles for …

Phenytoin sodium‐ameliorated gingival fibroblast aging is associated with autophagy

Y Kang, R Yang, Z Wei, D Zhu, T Tang… - Journal of …, 2020 - Wiley Online Library
Abstract Background and Objective Human gingival fibrolasts aging is an important cause of
periodontal disease. Phenytoin sodium (phenytoin) has a side effect of gingival hyperplasia …

Synthesis of Titanate Nanotube for Antibacterial and Tissue Regeneration Applications

LM Kassem, AH Zaki, AG El‑Deen, SI El‑Dek - Inorganic Chemistry …, 2024 - Elsevier
An increasingly crucial therapeutic issue revolves around treating bacterial infections in
chronic skin wounds that have developed resistance to antibiotics. Despite the current …

Aspectos clínicos e demográficos de pessoas com deficiência atendidas em uma clínica-escola de Odontologia

ETF da Silva, ELMS da Silva… - Revista da …, 2021 - revabeno.emnuvens.com.br
O objetivo deste artigo foi descrever as características clínicas e demográficas de pessoas
com deficiência atendidas em uma clínica-escola de Odontologia do Nordeste brasileiro …

Drug induced gingival enlargement-phenytoin: an overview and case report

N Dhalla, L Gopal, P Palwankar - Journal of Surgical Case …, 2024 - academic.oup.com
Gingival enlargement is a side effect of several different medication, including
immunosuppressants, anticonvulsants, and calcium channel blockers. It is an inflammatory …

Histological evaluation of wound healing by topical phenytoin application on extraction socket: an in vivo study in albino Wistar rats

M Christopher, A Fazal, MM Mehdi, D Anthoney… - Journal of Oral …, 2023 - jomos.org
Objective: To investigate the effects of topical phenytoin application on wound healing of
extraction socket of albino Wistar rats. Materials and methods: Thirty-six albino Wistar rats …