Decreased serotonergic activity has been implicated in anxiety and major depression, and
antidepressants directly or indirectly increase the long-term activity of the serotonin system …

In spite of promising preclinical results there is a decreasing number of new registered
medications in major depression. The main reason behind this fact is the lack of confirmation …

Epidemiological studies have revealed that mental disorders are highly comorbid; almost
half of the people with a mental disorder also meet the criteria of another disorder. The …

Since its theoretical inception, psychopathy has been considered by philosophers,
clinicians, theorists, and empirical researchers to be substantially and critically explained by …

Major depression and anxiety are highly prevalent and involve chronic dysregulation of
serotonin, but they remain poorly understood. Here, we review novel transcriptional (genetic …

This review focuses on current research developments in the study of gene by early life
stress (ELS) interactions and depression. ELS refers to aversive experiences during …

A genome-wide association (GWA) study of treatment outcomes (response and remission) of
selective serotonin reuptake inhibitors (SSRIs) was conducted using 529 subjects with major …

Background Prior exposure to stress is a risk factor for developing posttraumatic stress
disorder (PTSD) in response to trauma, yet the mechanisms by which this occurs are …

Background In women, low sexual desire and/or sexual arousal can lead to sexual
dissatisfaction and emotional distress, collectively defined as female sexual interest/arousal …

Abstract Hydrogen peroxide (H 2 O 2), as a common disinfectant, has been extensively used
in aquaculture. The toxicity of high ambient H 2 O 2 for gills and liver of fish has received …