Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

[HTML][HTML] Exercise and nutrition impact on osteoporosis and sarcopenia—the incidence of osteosarcopenia: a narrative review

SK Papadopoulou, K Papadimitriou, G Voulgaridou… - Nutrients, 2021 - mdpi.com
Osteoporosis and sarcopenia are diseases which affect the myoskeletal system and often
occur in older adults. They are characterized by low bone density and loss of muscle mass …

[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals

R Furrer, JA Hawley, C Handschin - Physiological Reviews, 2023 - journals.physiology.org
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

[HTML][HTML] Molecular mechanisms of muscle fatigue

D Constantin-Teodosiu, D Constantin - International journal of molecular …, 2021 - mdpi.com
Muscle fatigue (MF) declines the capacity of muscles to complete a task over time at a
constant load. MF is usually short-lasting, reversible, and is experienced as a feeling of …

A Laing distal myopathy–associated proline substitution in the β-myosin rod perturbs myosin cross-bridging activity

M Buvoli, GCK Wilson, A Buvoli… - Journal of Clinical …, 2024 - Am Soc Clin Investig
Proline substitutions within the coiled-coil rod region of the β-myosin gene (MYH7) are the
predominant mutations causing Laing distal myopathy (MPD1), an autosomal dominant …

[HTML][HTML] The effect of plyometric training on the speed, agility, and explosive strength performance in elite athletes

H Huang, WY Huang, CE Wu - Applied Sciences, 2023 - mdpi.com
The purpose of this study was to evaluate the speed, agility, and explosive strength
performance of elite basketball players over an 8-week plyometric training program. Fifteen …

[HTML][HTML] Endurance exercise-induced Fgf21 promotes skeletal muscle fiber conversion through TGF-β1 and p38 MAPK signaling pathway

X Luo, H Zhang, X Cao, D Yang, Y Yan, J Lu… - International Journal of …, 2023 - mdpi.com
Fgf21 has been identified as playing a regulatory role in muscle growth and function.
Although the mechanisms through which endurance training regulates skeletal muscle have …

[HTML][HTML] Finding the Goldilocks Zone of Mechanical Loading: A Comprehensive Review of Mechanical Loading in the Prevention and Treatment of Knee Osteoarthritis

J Jahn, QT Ehlen, CY Huang - Bioengineering, 2024 - mdpi.com
In this review, we discuss the interaction of mechanical factors influencing knee
osteoarthritis (KOA) and post-traumatic osteoarthritis (PTOA) pathogenesis. Emphasizing the …

[HTML][HTML] Remodeling of skeletal muscle myosin metabolic states in hibernating mammals

CTA Lewis, EG Melhedegaard, MM Ognjanovic… - Elife, 2024 - elifesciences.org
Hibernation is a period of metabolic suppression utilized by many small and large mammal
species to survive during winter periods. As the underlying cellular and molecular …

[HTML][HTML] Genome-Wide Association Study Identifies CDKN1A as a Novel Locus Associated with Muscle Fiber Composition

EA Semenova, H Zempo, E Miyamoto-Mikami… - Cells, 2022 - mdpi.com
Muscle fiber composition is associated with physical performance, with endurance athletes
having a high proportion of slow-twitch muscle fibers compared to power athletes …