Genomic testing for human health and disease across the life cycle: applications and ethical, legal, and social challenges
GA Bilkey, BL Burns, EP Coles, FL Bowman… - Frontiers in Public …, 2019 - frontiersin.org
The expanding use of genomic technologies encompasses all phases of life, from the
embryo to the elderly, and even the posthumous phase. In this paper, we present the …
embryo to the elderly, and even the posthumous phase. In this paper, we present the …
[HTML][HTML] A scoping study to explore the cost-effectiveness of next-generation sequencing compared with traditional genetic testing for the diagnosis of learning …
S Beale, D Sanderson, A Sanniti, Y Dundar… - Health Technology …, 2015 - europepmc.org
Background Learning disability (LD) is a serious and lifelong condition characterised by the
impairment of cognitive and adaptive skills. Some cases of LD with unidentified causes may …
impairment of cognitive and adaptive skills. Some cases of LD with unidentified causes may …
How physicians use array comparative genomic hybridization results to guide patient management in children with developmental delay
J Saam, J Gudgeon, E Aston, AR Brothman - Genetics in Medicine, 2008 - nature.com
Purpose: Array comparative genomic hybridization is an emerging test used clinically to
identify the etiology of children with developmental delay, yet little data are available …
identify the etiology of children with developmental delay, yet little data are available …
Array comparative genomic hybridization for diagnosis of developmental delay–an exploratory cost‐consequences analysis
A major application of array comparative genomic hybridization (aCGH) is to define a
specific cause in children with undiagnosed learning and developmental disability (LDD) …
specific cause in children with undiagnosed learning and developmental disability (LDD) …
[图书][B] Making genetics and genomics policy in Britain: from personal to population health
P Begley, S Sheard - 2022 - taylorfrancis.com
This important book traces the history of genetics and genomics policy in Britain. Detailing
the scientific, political, and economic factors that have informed policy and the development …
the scientific, political, and economic factors that have informed policy and the development …
Testing the Complex Child: CGH Array, WES, Clinical Exome, WGS
A Mallawaarachchi, F Collins - Current Pediatrics Reports, 2016 - Springer
Abstract Purpose of Review The purpose of this review was to compare existing strategies
for evaluation of complex paediatric patients with newer techniques. Comparative genomic …
for evaluation of complex paediatric patients with newer techniques. Comparative genomic …