Asthma in Hispanics. An 8-year update
FJ Rosser, E Forno, PJ Cooper… - American journal of …, 2014 - atsjournals.org
This review provides an update on asthma in Hispanics, a diverse group tracing their
ancestry to countries previously under Spanish rule. A marked variability in the prevalence …
ancestry to countries previously under Spanish rule. A marked variability in the prevalence …
The genetics of Mexico recapitulates Native American substructure and affects biomedical traits
Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-
wide variation from this region remain largely uncharacterized. We studied genomic …
wide variation from this region remain largely uncharacterized. We studied genomic …
Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma
Asthma is a chronic and genetically complex respiratory disease that affects over 300 million
people worldwide. Here, we report a genome-wide analysis for asthma using data from the …
people worldwide. Here, we report a genome-wide analysis for asthma using data from the …
Genetic diversity in populations across Latin America: implications for population and medical genetic studies
Hispanic/Latino (H/L) populations, although linked by culture and aspects of shared history,
reflect the complexity of history and migration influencing the Americas. The original …
reflect the complexity of history and migration influencing the Americas. The original …
Genetic ancestry influences asthma susceptibility and lung function among Latinos
Background Childhood asthma prevalence and morbidity varies among Latinos in the
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …
Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans …
Background Asthma is a complex disease with both genetic and environmental causes.
Genome-wide association studies of asthma have mostly involved European populations …
Genome-wide association studies of asthma have mostly involved European populations …
Genome-wide methylation data mirror ancestry information
Background Genetic data are known to harbor information about human demographics, and
genotyping data are commonly used for capturing ancestry information by leveraging …
genotyping data are commonly used for capturing ancestry information by leveraging …
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations
AM Levin, RA Mathias, L Huang, LA Roth… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: IgE is both a marker and mediator of allergic inflammation. Despite
reported differences in serum total IgE levels by race-ethnicity, African American and Latino …
reported differences in serum total IgE levels by race-ethnicity, African American and Latino …
Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis
Background Allergic rhinitis is a common disease whose genetic basis is incompletely
explained. We report an integrated genomic analysis of allergic rhinitis. Methods We …
explained. We report an integrated genomic analysis of allergic rhinitis. Methods We …
An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos
Background Asthma is a common but complex disease with racial/ethnic differences in
prevalence, morbidity, and response to therapies. Objective We sought to perform an …
prevalence, morbidity, and response to therapies. Objective We sought to perform an …