Zinc-finger proteins in health and disease

M Cassandri, A Smirnov, F Novelli, C Pitolli… - Cell death …, 2017 - nature.com
Zinc-finger proteins (ZNFs) are one of the most abundant groups of proteins and have a
wide range of molecular functions. Given the wide variety of zinc-finger domains, ZNFs are …

Periostin: a matricellular protein with multiple functions in cancer development and progression

L González-González, J Alonso - Frontiers in oncology, 2018 - frontiersin.org
Tumor microenvironment is considered nowadays as one of the main players in cancer
development and progression. Tumor microenvironment is highly complex and consists of …

Oral mucosal organoids as a potential platform for personalized cancer therapy

E Driehuis, S Kolders, S Spelier, K Lõhmussaar… - Cancer discovery, 2019 - AACR
Previous studies have described that tumor organoids can capture the diversity of defined
human carcinoma types. Here, we describe conditions for long-term culture of human …

Profiling early head and neck cancer

KD Hunter, EK Parkinson, PR Harrison - Nature Reviews Cancer, 2005 - nature.com
Head and neck squamous-cell carcinoma (HNSCC) is the sixth most common cancer
worldwide and, disappointingly, survival rates are not improving. Moreover, HNSCC has a …

CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis

P Baumann, N Cremers, F Kroese, G Orend… - Cancer research, 2005 - AACR
The glycosylphosphatidylinositol-anchored membrane protein CD24 functions as an
adhesion molecule for P-selectin and L1 and plays a role in B-cell development and …

Gene expression profiling identifies genes predictive of oral squamous cell carcinoma

C Chen, E Méndez, J Houck, W Fan… - … Biomarkers & Prevention, 2008 - AACR
Oral squamous cell carcinoma (OSCC) is associated with substantial mortality and
morbidity. To identify potential biomarkers for the early detection of invasive OSCC, we …

Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer

Y Kudo, I Ogawa, S Kitajima, M Kitagawa, H Kawai… - Cancer research, 2006 - AACR
Head and neck squamous cell carcinoma (HNSCC) is one of the most common types of
human cancer. Typically, HNSCC cells show persistent invasion that frequently leads to …

Predicting hub genes associated with cervical cancer through gene co-expression networks

SP Deng, L Zhu, DS Huang - IEEE/ACM Transactions on …, 2015 - ieeexplore.ieee.org
Cervical cancer is the third most common malignancy in women worldwide. It remains a
leading cause of cancer-related death for women in developing countries. In order to …

Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays

R Grützmann, C Pilarsky, O Ammerpohl, J Luttges… - Neoplasia, 2004 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) remains an important cause of malignancy-
related death and is the eighth most common cancer with the lowest overall 5-year relative …

Selection and validation of differentially expressed genes in head and neck cancer

MA Kuriakose, WT Chen, ZM He, AG Sikora… - Cellular and Molecular …, 2004 - Springer
We applied a robust combinatorial (multi-test) approach to microarray data to identify genes
consistently up-or down-regulated in head and neck squamous cell carcinoma (HNSCC) …