CD44 as a tumor biomarker and therapeutic target
H Xu, M Niu, X Yuan, K Wu, A Liu - Experimental hematology & oncology, 2020 - Springer
CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
CD44: a multifunctional mediator of cancer progression
CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated
as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …
as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …
The role of cancer stem cells in radiation resistance
CR Arnold, J Mangesius, II Skvortsova… - Frontiers in …, 2020 - frontiersin.org
Cancer stem cells (CSC) are a distinct subpopulation within a tumor. They are able to self-
renew and differentiate and possess a high capability to repair DNA damage, exhibit low …
renew and differentiate and possess a high capability to repair DNA damage, exhibit low …
Hyaluronic acid-functionalized lipoplexes and polyplexes as emerging nanocarriers for receptor-targeted cancer therapy
J Chandra, N Molugulu, S Annadurai, S Wahab… - Environmental …, 2023 - Elsevier
Cancer is an intricate disease that develops as a response to a combination of hereditary
and environmental risk factors, which then result in a variety of changes to the genome. The …
and environmental risk factors, which then result in a variety of changes to the genome. The …
[HTML][HTML] Advanced hitchhiking nanomaterials for biomedical applications
Hitchhiking, a recently developed bio-inspired cargo delivery system, has been harnessed
for diverse applications. By leveraging the interactions between nanoparticles and …
for diverse applications. By leveraging the interactions between nanoparticles and …
Osteopontin: a key regulator of tumor progression and immunomodulation
Simple Summary Anti-PD-1/PD-L1 and anti-CTLA-4-based immune checkpoint blockade
(ICB) immunotherapy have recently emerged as a breakthrough in human cancer treatment …
(ICB) immunotherapy have recently emerged as a breakthrough in human cancer treatment …
[HTML][HTML] Tumor microenvironment in head and neck squamous cell carcinoma: Functions and regulatory mechanisms
G Wang, M Zhang, M Cheng, X Wang, K Li, J Chen… - Cancer Letters, 2021 - Elsevier
The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …
Lung cancer stem cell markers as therapeutic targets: an update on signaling pathways and therapies
Y Zheng, L Wang, L Yin, Z Yao, R Tong, J Xue… - Frontiers in …, 2022 - frontiersin.org
Cancer stem cells, a relatively small group of self-renewing cancer cells, were first isolated
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …
Engineered liposomes in interventional theranostics of solid tumors
N Kommineni, R Chaudhari, J Conde… - ACS Biomaterials …, 2023 - ACS Publications
Engineered liposomal nanoparticles have unique characteristics as cargo carriers in cancer
care and therapeutics. Liposomal theranostics have shown significant progress in preclinical …
care and therapeutics. Liposomal theranostics have shown significant progress in preclinical …
The role of CD44 in pathological angiogenesis
L Chen, C Fu, Q Zhang, C He, F Zhang… - The FASEB …, 2020 - Wiley Online Library
Angiogenesis is required for normal development and occurs as a pathological step in a
variety of disease settings, such as cancer, ocular diseases, and ischemia. Recent studies …
variety of disease settings, such as cancer, ocular diseases, and ischemia. Recent studies …