CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …

CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated
as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess …

Cancer stem cells (CSC) are a distinct subpopulation within a tumor. They are able to self-
renew and differentiate and possess a high capability to repair DNA damage, exhibit low …

Cancer is an intricate disease that develops as a response to a combination of hereditary
and environmental risk factors, which then result in a variety of changes to the genome. The …

Hitchhiking, a recently developed bio-inspired cargo delivery system, has been harnessed
for diverse applications. By leveraging the interactions between nanoparticles and …

Simple Summary Anti-PD-1/PD-L1 and anti-CTLA-4-based immune checkpoint blockade
(ICB) immunotherapy have recently emerged as a breakthrough in human cancer treatment …

The tumor microenvironment has been recently reported to play a pivotal role in sustaining
tumor cells survival and protecting them from immunotherapy and chemotherapy-induced …

Cancer stem cells, a relatively small group of self-renewing cancer cells, were first isolated
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …

Engineered liposomal nanoparticles have unique characteristics as cargo carriers in cancer
care and therapeutics. Liposomal theranostics have shown significant progress in preclinical …

Angiogenesis is required for normal development and occurs as a pathological step in a
variety of disease settings, such as cancer, ocular diseases, and ischemia. Recent studies …