Cooperative effects on the compaction of DNA fragments by the nucleoid protein H-NS and the crowding agent PEG probed by magnetic tweezers
M Cristofalo, CA Marrano, D Salerno, R Corti… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Background DNA bridging promoted by the H-NS protein, combined with the compaction
induced by cellular crowding, plays a major role in the structuring of the E. coli genome …
induced by cellular crowding, plays a major role in the structuring of the E. coli genome …
Effects of the size and concentration of depleting agents on the stabilization of the double-helix structure and DNA condensation: A single molecule force spectroscopy …
RM de Oliveira, MS Rocha - Chemical Physics Letters, 2024 - Elsevier
We perform a single molecule force spectroscopy study to characterize the role of the size
(molecular weight) and concentration of depleting agents on DNA condensation and on the …
(molecular weight) and concentration of depleting agents on DNA condensation and on the …
Real-time label-free analysis of the thermostability of DNA structures using GelRed
YY Hao, L Liu, LH Zhang, QL Huang, F Wang… - Nuclear Science and …, 2018 - Springer
In biological systems, conformational transformations of nucleic acids play critical roles in
genetic regulation. However, it remains a tricky task to design and optimize specific labeling …
genetic regulation. However, it remains a tricky task to design and optimize specific labeling …
Doxorubicin hinders DNA condensation promoted by the protein bovine serum albumin (BSA)
In this work, we have studied the interaction between the anticancer drug doxorubicin (doxo)
and condensed DNA, using optical tweezers. To perform this task, we use the protein bovine …
and condensed DNA, using optical tweezers. To perform this task, we use the protein bovine …
[图书][B] DNA Interactions with Drugs and Other Small Ligands: Single Molecule Approaches and Techniques
MS Rocha - 2023 - books.google.com
DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and
Techniques provides the reader with all the main information, a" state-of-the-art" of sorts and …
Techniques provides the reader with all the main information, a" state-of-the-art" of sorts and …
Observation of Ethanol-Induced Condensation and Decondensation Processes at a Single-DNA Molecular Level in Microfluidic Devices Equipped with a Rapid …
Conformational transitions from secondary (eg, B-to A-form DNA) to higher-order (eg, coil to
globule) transitions play important roles in genome expression and maintenance. Several …
globule) transitions play important roles in genome expression and maintenance. Several …
Nanomechanics of DNA and DNA-ligand interactions: focus on structural polymorphism and DNA condensation
M Cristofalo - 2019 - boa.unimib.it
In the last few decades, the constant development of novel microscopy techniques have
created the basis for a new paradigm in the field of biophysics. Single-molecule techniques …
created the basis for a new paradigm in the field of biophysics. Single-molecule techniques …