Remote ischaemic preconditioning: underlying mechanisms and clinical application

DJ Hausenloy, DM Yellon - Cardiovascular research, 2008 - academic.oup.com
Remote ischaemic preconditioning (RIPC) represents a strategy for harnessing the body's
endogenous protective capabilities against the injury incurred by ischaemia and …

Cardioprotection by remote ischemic conditioning and its signal transduction

P Kleinbongard, A Skyschally, G Heusch - Pflügers Archiv-European …, 2017 - Springer
Cardioprotective strategies aim to salvage myocardium from ischemia/reperfusion injury and
to reduce infarct size and its consequences. Different stimuli, acting at sites remote from the …

[HTML][HTML] Delayed remote ischemic preconditioning confersrenoprotection against septic acute kidney injury via exosomal miR-21

T Pan, P Jia, N Chen, Y Fang, Y Liang, M Guo… - Theranostics, 2019 - ncbi.nlm.nih.gov
Sepsis is a common and life-threatening systemic disorder, often leading to acute injury of
multiple organs. Here, we show that remote ischemic preconditioning (rIPC), elicited by brief …

Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial

DJ Hausenloy, PK Mwamure, V Venugopal, J Harris… - The Lancet, 2007 - thelancet.com
Background Whether remote ischaemic preconditioning, an intervention in which brief
ischaemia of one tissue or organ protects remote organs from a sustained episode of …

MicroRNA-144 is a circulating effector of remote ischemic preconditioning

J Li, S Rohailla, N Gelber, J Rutka, N Sabah… - Basic research in …, 2014 - Springer
Remote ischemic preconditioning (rIPC) induced by cycles of transient limb ischemia and
reperfusion is a powerful cardioprotective strategy with additional pleiotropic effects …

Remote ischemic preconditioning: a novel protective method from ischemia reperfusion injury—a review

N Tapuria, Y Kumar, MM Habib, MA Amara… - Journal of Surgical …, 2008 - Elsevier
BACKGROUND: Restoration of blood supply to an organ after a critical period of ischemia
results in parenchymal injury and dysfunction of the organ referred to as reperfusion injury …

Current status of experimental animal skin flap models: ischemic preconditioning and molecular factors

JH Lee, HJ You, TY Lee, HJ Kang - International journal of molecular …, 2022 - mdpi.com
Skin flaps are necessary in plastic and reconstructive surgery for the removal of skin cancer,
wounds, and ulcers. A skin flap is a portion of skin with its own blood supply that is partially …

Translation of remote ischaemic preconditioning into clinical practice

RK Kharbanda, TT Nielsen, AN Redington - The Lancet, 2009 - thelancet.com
Reduction of the burden of ischaemia-reperfusion injury is the aim of most treatments for
cardiovascular and cerebrovascular disease. Although many strategies have proven benefit …

Acute kidney injury and extrarenal organ dysfunction: new concepts and experimental evidence.

SC Yap, HT Lee - Anesthesiology, 2012 - europepmc.org
Acute kidney injury (AKI) is a frequent complication in the intensive care unit with limited
therapeutic modalities. Although survival from isolated AKI has improved with recent …

Plasma exosomes induced by remote ischaemic preconditioning attenuate myocardial ischaemia/reperfusion injury by transferring miR-24

W Minghua, G Zhijian, H Chahua, L Qiang… - Cell death & …, 2018 - nature.com
Remote ischaemic preconditioning (RIPC) is well known to protect the myocardium against
ischaemia/reperfusion injury (IRI). Exosomes are small extracellular vesicles that have …