Systemic immune activation has emerged as an essential component of the
immunopathogenesis of HIV. It not only leads to faster disease progression, but also to …

Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …

Even after attainment of sustained viral suppression following implementation of highly
active antiretroviral therapy, HIV-infected persons continue to experience persistent, low …

Introduction Preeclampsia and HIV/AIDS are inflammatory conditions that contribute
significantly to adverse maternal and foetal outcomes. The immune reconstitution effects of …

Patients infected with the human immunodeficiency virus (HIV) have an increased
cardiovascular risk. Although initially this increased risk was attributed to metabolic …

Intracellular pathogens such as the human immunodeficiency virus, hepatitis C and B or
Epstein–Barr virus often cause chronic viral infections in humans. Persistence of these …

Human immunodeficiency virus type 1 (HIV-1) infection triggers rapid induction of multiple
innate cytokines including type I interferons, which play important roles in viral control and …

We evaluated immune biomarker profiles in human immunodeficiency virus (HIV)–infected
adults (n= 398) from 5 African countries. Although all biomarkers decreased after …

Despite the widespread success of combined antiretroviral therapy (cART) in suppressing
viremia, the prevalence of human immunodeficiency virus (HIV)-associated neurological …

HIV-infected persons not only have higher rates of smoking than the general population, but
are also unusually vulnerable to the associated adverse health effects, both infective and …