Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …

Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading
cause of cancer-related deaths worldwide. Although the prognosis of patients with HCC is …

A major challenge in understanding vertebrate embryogenesis is the lack of topographical
transcriptomic information that can help correlate microenvironmental cues within the …

Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic
acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor …

The burgeoning field of anaplastic lymphoma kinase (ALK) in cancer encompasses many
cancer types, from very rare cancers to the more prevalent non-small-cell lung cancer …

Although glycosaminoglycans contribute to diverse physiological processes,,,, an
understanding of their molecular mechanisms has been hampered by the inability to access …

Continuous efforts have been devoted to unraveling the biophysiology and development of
the human fetal adrenal cortex, which is structurally and functionally unique from other …

RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and
differentiation. In addition, RTKs reveal oncogenic potential when their kinase activities are …

The midkine (MK) family consists of only two members, namely heparin-binding growth
factors MK and pleiotrophin (PTN). During embryogenesis, MK is highly expressed in the …

Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide. The
HCC diagnosis is usually achieved by biomarkers, which can also help in prognosis …