Megakaryocytes are hematopoietic cells, which are responsible for the production of blood
platelets. The traditional view of megakaryopoiesis describes the cellular journey from …

Oysters, the common name for a number of different bivalve molluscs, are the worldwide
aquaculture species and also play vital roles in the function of ecosystem. As invertebrate …

Hematopoiesis–the process by which blood cells are formed–has been studied intensely for
over a century using a variety of model systems. There is conservation of the overall …

Establishment and maintenance of the blood system relies on self-renewing hematopoietic
stem cells (HSCs) that normally reside in small numbers in the bone marrow niche of adult …

Haematopoietic stem cell (HSC) homeostasis is tightly controlled by growth factors,
signalling molecules and transcription factors. Definitive HSCs derived during …

Starting with multipotent progenitors, hematopoietic lineages are specified by lineage-
restricted transcription factors. The transcription factors that determine the decision between …

The Drosophila lymph gland, the larval hematopoietic organ comprised of prohemocytes
and mature hemocytes, has been a valuable model for understanding mechanisms …

Blood vessels perfuse all tissues in the body and mediate vital metabolic exchange between
tissues and blood. Increasing evidence, however, points to a direct role for paracrine …

Progressive advances using zebrafish as a model organism have provided hematologists
with an additional genetic system to study blood cell formation and hematological …

In contrast to higher vertebrates, most fish species hatch at the embryonic stage of life.
Consequently, they have to defend against a variety of micro-organisms living in their …