Metabolic engineering for the synthesis of polyesters: A 100-year journey from polyhydroxyalkanoates to non-natural microbial polyesters

SY Choi, MN Rhie, HT Kim, JC Joo, IJ Cho, J Son… - Metabolic …, 2020 - Elsevier
As concerns increase regarding sustainable industries and environmental pollutions caused
by the accumulation of non-degradable plastic wastes, bio-based polymers, particularly …

Zymomonas mobilis as a model system for production of biofuels and biochemicals

S Yang, Q Fei, Y Zhang, LM Contreras… - Microbial …, 2016 - Wiley Online Library
Zymomonas mobilis is a natural ethanologen with many desirable industrial biocatalyst
characteristics. In this review, we will discuss work to develop Z. mobilis as a model system …

From zero to hero—design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

J Becker, O Zelder, S Häfner, H Schröder… - Metabolic …, 2011 - Elsevier
Here, we describe the development of a genetically defined strain of l-lysine hyperproducing
Corynebacterium glutamicum by systems metabolic engineering of the wild type …

Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds

A Rodriguez, JA Martnez, N Flores, A Escalante… - Microbial cell …, 2014 - Springer
The production of aromatic amino acids using fermentation processes with recombinant
microorganisms can be an advantageous approach to reach their global demands. In …

Metabolic engineering of microorganisms for biofuel production

P Majidian, M Tabatabaei, M Zeinolabedini… - … and Sustainable Energy …, 2018 - Elsevier
Microorganisms directly and indirectly contribute to production of diverse biofuels.
Heterotrophic microorganisms are being used for commercial production of biofuels such as …

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …

DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers

YK Jung, TY Kim, SJ Park… - Biotechnology and …, 2010 - Wiley Online Library
Polylactic acid (PLA) is a promising biomass‐derived polymer, but is currently synthesized
by a two‐step process: fermentative production of lactic acid followed by chemical …

Genome-scale models of bacterial metabolism: reconstruction and applications

M Durot, PY Bourguignon… - FEMS microbiology …, 2008 - academic.oup.com
Genome-scale metabolic models bridge the gap between genome-derived biochemical
information and metabolic phenotypes in a principled manner, providing a solid …

Thermophilic lignocellulose deconstruction

SE Blumer-Schuette, SD Brown… - FEMS microbiology …, 2014 - academic.oup.com
Thermophilic microorganisms are attractive candidates for conversion of lignocellulose to
biofuels because they produce robust, effective, carbohydrate-degrading enzymes and …