Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
J Zhu, S Wang, D Yang, W Xu, H Qian - Journal of Nanobiotechnology, 2023 - Springer
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
Exosomes in cardiovascular disease: from mechanism to therapeutic target
AB Reiss, S Ahmed, M Johnson, U Saeedullah… - Metabolites, 2023 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. In
recent decades, clinical research has made significant advances, resulting in improved …
recent decades, clinical research has made significant advances, resulting in improved …
Extracellular vesicles: the future of diagnosis in solid organ transplantation?
N Romero-García, J Huete-Acevedo… - International Journal of …, 2023 - mdpi.com
Solid organ transplantation (SOT) is a life-saving treatment for end-stage organ failure, but it
comes with several challenges, the most important of which is the existing gap between the …
comes with several challenges, the most important of which is the existing gap between the …
Basic pathogenic mechanisms and epigenetic players promoted by extracellular vesicles in vascular damage
Both progression from the early pathogenic events to clinically manifest cardiovascular
diseases (CVD) and cancer impact the integrity of the vascular system. Pathological …
diseases (CVD) and cancer impact the integrity of the vascular system. Pathological …
Role of miR‐15a‐5p and miR‐199a‐3p in the inflammatory pathway regulated by NF‐κB in experimental and human atherosclerosis
P González‐López, M Álvarez‐Villarreal… - Clinical and …, 2023 - Wiley Online Library
Abstract Background Cardiovascular diseases (CVDs) prevalence has significantly
increased in the last decade and atherosclerosis development is the main trigger …
increased in the last decade and atherosclerosis development is the main trigger …
Vascular calcification: from the perspective of crosstalk
S Yang, Z Zeng, Q Yuan, Q Chen, Z Wang, H Xie… - Molecular …, 2023 - Springer
Vascular calcification (VC) is highly correlated with cardiovascular disease morbidity and
mortality, but anti-VC treatment remains an area to be tackled due to the ill-defined …
mortality, but anti-VC treatment remains an area to be tackled due to the ill-defined …
[HTML][HTML] Extracellular vesicles in atherosclerosis and vascular calcification: The versatile non-coding RNAs from endothelial cells and vascular smooth muscle cells
F Yu, Y Duan, C Liu, H Huang, X Xiao, Z He - Frontiers in Medicine, 2023 - ncbi.nlm.nih.gov
Atherosclerosis (AS) is characterized by the accumulation of lipids, fibrous elements, and
calcification in the innermost layers of arteries. Vascular calcification (VC), the deposition of …
calcification in the innermost layers of arteries. Vascular calcification (VC), the deposition of …
[HTML][HTML] circRNA, a novel diagnostic biomarker for coronary heart disease
X Tong, X Zhao, X Dang, Y Kou, J Kou - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Objective: This study aimed to identify the potential diagnostic biomarkers of coronary heart
disease (CHD) from exosome-derived circRNA. Methods: The microarray data of circRNA …
disease (CHD) from exosome-derived circRNA. Methods: The microarray data of circRNA …
Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease
JP Flemming, PJ Wermuth, MG Mahoney - Journal of Investigative …, 2023 - Elsevier
The recent discovery of extracellular vesicles (EVs) carrying cargo consisting of various
bioactive macromolecules that can modulate the phenotype of recipient target cells has …
bioactive macromolecules that can modulate the phenotype of recipient target cells has …
Identification of microRNA biomarkers simultaneously expressed in circulating extracellular vesicles and atherosclerotic plaques
F Brandes, AS Meidert, B Kirchner, M Yu… - Frontiers in …, 2024 - frontiersin.org
Background Atherosclerosis is a widespread disorder of the cardiovascular system. The
early detection of plaques by circulating biomarkers is highly clinically relevant to prevent …
early detection of plaques by circulating biomarkers is highly clinically relevant to prevent …