Modulating the neuromodulators: dopamine, serotonin, and the endocannabinoid system
Dopamine (DA), serotonin (5-hydroxytryptamine, 5-HT), and endocannabinoids (ECs) are
key neuromodulators involved in many aspects of motivated behavior, including reward …
key neuromodulators involved in many aspects of motivated behavior, including reward …
Serotonergic modulation of the activity of mesencephalic dopaminergic systems: therapeutic implications
P De Deurwaerdère, G Di Giovanni - Progress in neurobiology, 2017 - Elsevier
Since their discovery in the mammalian brain, it has been apparent that serotonin (5-HT)
and dopamine (DA) interactions play a key role in normal and abnormal behavior …
and dopamine (DA) interactions play a key role in normal and abnormal behavior …
Serotonergic neurons signal reward and punishment on multiple timescales
Serotonin's function in the brain is unclear. One challenge in testing the numerous
hypotheses about serotonin's function has been observing the activity of identified …
hypotheses about serotonin's function has been observing the activity of identified …
The roles of dopamine and serotonin, and of their receptors, in regulating sleep and waking
JM Monti, H Jantos - Progress in brain research, 2008 - Elsevier
Based on electrophysiological, neurochemical and neuropharmacological approaches, it is
currently accepted that serotonin (5-HT) and dopamine (DA) function to promote waking (W) …
currently accepted that serotonin (5-HT) and dopamine (DA) function to promote waking (W) …
Meta-learning in reinforcement learning
N Schweighofer, K Doya - Neural Networks, 2003 - Elsevier
Meta-parameters in reinforcement learning should be tuned to the environmental dynamics
and the animal performance. Here, we propose a biologically plausible meta-reinforcement …
and the animal performance. Here, we propose a biologically plausible meta-reinforcement …
Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions
BP Guiard, M El Mansari, Z Merali… - International Journal of …, 2008 - academic.oup.com
Anatomical studies have established the existence of reciprocal relationships between the
main population of monoamine, serotonin (5-HT), norepinephrine (NE) and dopamine (DA) …
main population of monoamine, serotonin (5-HT), norepinephrine (NE) and dopamine (DA) …
Origin and functional role of the extracellular serotonin in the midbrain raphe nuclei
There is considerable interest in the regulation of the extracellular compartment of the
transmitter serotonin (5-hydroxytryptamine, 5-HT) in the midbrain raphe nuclei because it …
transmitter serotonin (5-hydroxytryptamine, 5-HT) in the midbrain raphe nuclei because it …
Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems
S Manta, M El Mansari, G Debonnel… - International Journal of …, 2013 - academic.oup.com
Vagus nerve stimulation (VNS) is an adjunctive treatment for resistant epilepsy and
depression. Electrophysiological recordings in the rat brain have already shown that chronic …
depression. Electrophysiological recordings in the rat brain have already shown that chronic …
Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus
K Nakamura, M Matsumoto… - Journal of Neuroscience, 2008 - Soc Neuroscience
The dopamine system has been thought to play a central role in guiding behavior based on
rewards. Recent pharmacological studies suggest that another monoamine …
rewards. Recent pharmacological studies suggest that another monoamine …
Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil
WM Qu, ZL Huang, XH Xu, N Matsumoto… - Journal of …, 2008 - Soc Neuroscience
Modafinil is a wake-promoting compound with low abuse potential used in the treatment of
narcolepsy. Although the compound is reported to affect multiple neurotransmitter systems …
narcolepsy. Although the compound is reported to affect multiple neurotransmitter systems …