Transition metals, which are of diversity in their bonding orbitals, have a variety of significant
oxidation states and more complex chemical properties compared to the main group metals …

Conspectus Catalytic intermolecular hydroamination of alkenes is an atom-and step-
economical method for the synthesis of amines, which have important applications as …

A visible-light photoredox-catalyzed method is reported that enables the coupling between
benzylic C–H substrates and N–H azoles. Classically, medicinally relevant N-benzyl azoles …

The straightforward construction of stereogenic centers bearing unprotected functional
groups, as in nature, has been a persistent pursuit in synthetic chemistry. Abundant …

Dicarboxylic acids and derivatives are important building blocks in organic synthesis,
biochemistry, and the polymer industry. Although catalytic dicarboxylation with CO2 …

Synergistic catalysis has emerged as one of the most powerful tools for stereodivergent
formation of Csp3− Csp3 bonds bearing vicinal stereocenters. Despite the many successes …

Chiral N-cyclopropyl pyrazoles and structurally related heterocycles are prepared using an
earth-abundant copper catalyst under mild reaction conditions with high regio-, diastereo …

Transition metal-catalyzed asymmetric hydrofunctionalizations of unsaturated bonds via π-
ƞ3 substitution have emerged as a reliable method to construct stereogenic centers, and …

Pd-catalyzed sequential hydroamination of readily available 1, 3-enynes is reported. The
redox-neutral process provides an efficient route to synthesize a broad scope of …

As an advance in hydrofunctionalization, we herein report that alcohols add to 1, 3-dienes
with high regio-and enantioselectivity. Using Ni-DuPhos, we access enantioenriched allylic …