Myoglobin is a well-characterized, cytoplasmic hemoprotein that is expressed primarily in
cardiomyocytes and oxidative skeletal muscle fibers. However, recent studies also suggest …

Brown adipose tissue (BAT) plays an important role in energy homeostasis by generating
heat from chemical energy via uncoupled oxidative phosphorylation. Besides its high …

Despite the success of highly active antiretroviral therapy (HAART), integrated HIV-1 proviral
DNA cannot be eradicated from an infected individual. HAART is not able to eliminate …

Although Sp1 is known to undergo posttranslational modifications such as phosphorylation,
glycosylation, acetylation, sumoylation, and ubiquitination, little is known about the possible …

We present here EKPD (http://ekpd. biocuckoo. org), a hierarchical database of eukaryotic
protein kinases (PKs) and protein phosphatases (PPs), the key molecules responsible for …

Abstract Cheliensisin A (Chel A), as a novel styryl-lactone isolated from Goniothalamus
cheliensis Hu, has been demonstrated to have an inhibition of EGF-induced Cl41 cell …

Cardiac hypertrophy develops in response to a variety of cardiovascular stresses and results
in activation of numerous signaling cascades and proteins. In the present study, we …

A high-glucose diet (HGD) is associated with the development of metabolic diseases that
decrease life expectancy, including obesity and type-2 diabetes (T2D); however, the …

The proto-oncogene c-Jun plays an important role in regulating tumor progression. We
previously reported that the serine/threonine phosphatase calcineurin (CaN, also called …

Background: Cancer treatment has recently shifted towards metabolic approaches aimed at
enhancing therapeutic efficacy. Somewhat surprisingly, a known regulator of energy …