Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …

Due to biological and medicinal properties of pyranopyrazoles, synthesis of these bioactive
heterocycles has attracted the interest of medicinal and organic chemists. This review …

We report a new pathway to synthesize pyrano [2, 3-c] pyrazoles and their binding mode to
p38 MAP kinase. Pyrano [2, 3-c] pyrazole derivatives have been prepared through a four …

An eco-friendly approach was conducted for synthesizing pyrano [2, 3-c] pyrazoles M1-M25
via a one-pot reaction of hydrazine hydrate 99%, ethyl acetoacetate or diethyl malonate …

The current work involves synthesis of 6-amino-4-(4-hydroxyl-3-methoxyphenyl)-3-methyl-1-
phenyl-1, 4- dihydropyrano [2, 3-c] pyrazole-5-carbonitrile (2) by condensation of 2-(4 …

Innovative therapeutic heterocycles having precisely thiadiazolyl-pyranopyrazole fragments
were prepared by using the ecofriendly synthetic route. Entire compounds formed in …

The novel naturally based magnetic biochar/Fe 3 O 4–TiO 2 nanocatalyst was developed,
characterised, and used to manufacture biologically active dihydropyrano-[2, 3-c]-pyrazole …

From a medical point of view lot of existing antibiotics became unusable because microbial
gained strong antibiotic resistance. The combination of two compounds in one core may …

Nitrogen based heterocycles display an impressive repertoire of biological activities,
including antioxidant, antimicrobial, anti-tuberculosis, analgesic, anti-inflammatory, anti-viral …

Background: Many pyrano [2, 3-c] pyrazole derivatives display diverse biological activities
and some of them are known as anticancer, analgesic, anticonvulsant, antimicrobial …