Pulmonary hypertension (PH) is a progressive lethal disease, which is characterized by
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …

Hyperuricemia is an essential causal risk factor for gout and is associated with
cardiometabolic diseases. Given the limited contribution of East Asian ancestry to genome …

Pulmonary hypertension is a rare, ostensibly incurable, and etiologically diverse disease
with an unacceptably high 5-year mortality rate (≈ 50%), worse than many cancers …

Previous studies have suggested a correlation between uric acid (UA) and lung lesion in
some diseases. However, it remains unknown whether UA contributes to the lung injury in …

Introduction Idiopathic pulmonary hypertension (IPAH) is a rare disease that causes severe
morbidity and mortality despite advances in treatment management. Evaluating the …

Background Previous studies have shown that serum uric acid (UA) levels are correlated
with the severity of idiopathic pulmonary arterial hypertension (IPAH) and are predictors of …

Background Observational studies have suggested a correlation between hyperuricemia
and pulmonary arterial hypertension (PAH), yet the causal relationship remains uncertain …

Chronic mountain sickness (CMS) is a high altitude complication with high rates of morbidity
and mortality. CMS is characterized by high-altitude polycythemia (HAPC) and high-altitude …

Recent studies suggest that pregnancy may not be absolutely contraindicated in women
with moderate pulmonary hypertension. We aimed to evaluate the long-term outcomes of …

Increased oxidative stress and high uric acid are implicated in the pathogenesis of
pulmonary hypertension (PH). This provides opportunity to benefit from drugs like allopurinol …