In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

The main constituent of an ultrasound contrast agent (UCA) is gas-filled microbubbles. An
average UCA contains billions per ml. These microbubbles are excellent ultrasound …

Molecular imaging using ultrasound makes use of targeted microbubbles. In this study we
investigated whether these microbubbles could also be used to induce sonoporation in …

The merits of ultrasound contrast agents (UCAs) were already known in the 1960s. It was,
however, not until the 1990s that UCAs were clinically approved and marketed. In these …

The occurrence of nonspherical oscillations (or surface modes) of coated microbubbles,
used as ultrasound contrast agents in medical imaging, is investigated using ultra–high …

Acoustic super-resolution imaging has allowed the visualization of microvascular structure
and flow beyond the diffraction limit using standard clinical ultrasound systems through the …

Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing
the cell membrane permeability. To aid development of a safe and effective therapeutic …

The integration of therapeutic interventions with diagnostic imaging has been recognized as
one of the next technological developments that will have a major impact on medical …

Lipid-coated microbubbles are used clinically as contrast agents for ultrasound imaging and
are being developed for a variety of therapeutic applications. The lipid encapsulation and …