Freely accessible chemical database resources of compounds for in silico drug discovery

JF Yang, D Wang, C Jia, M Wang… - Current Medicinal …, 2019 - ingentaconnect.com
Background: In silico drug discovery has been proved to be a solidly established key
component in early drug discovery. However, this task is hampered by the limitation of …

[PDF][PDF] Prediction of anticancer activity of potential anticancer compounds using pass online software

L Dash, N Sharma, M Vyas, R Kumar, R Kumar… - Plant …, 2020 - plantarchives.org
Background: Cancer is defined as abnormal and uncontrolled division of body's own cell.
The Anticancer drug will either kill the cancerous cell or modify their growth. In the present …

Preclinical studies to enable first in human clinical trials

R Chopra, FI Raynaud - Phase I Oncology Drug Development, 2020 - Springer
Drug discovery is a multidisciplinary process which requires a coordinated effort to deliver a
drug candidate with appropriate pharmaceutical properties and a clear therapeutic …

[PDF][PDF] Design and delivery of genes encoding oncotoxic proteins for cancer therapy

P Hauswirth - 2022 - edoc.unibas.ch
Development of cancer depends on mutations within the organisms' own cells. Mutations of
random loci within the genome, affecting a wide variety of genes might lead to cancer. The …