Sepsis is one of the leading causes of deaths world-wide and yet there are no therapies
available other than ICU treatment. The patient outcome is determined by a complex …

Failures of highly touted trials have caused experts to call for re-evaluation of the current
approach toward sepsis. New research has revealed key pathogenic mechanisms; autopsy …

Objective: The objective of this study was to determine whether persistent lymphopenia on
the fourth day following the diagnosis of sepsis predicts mortality. Methods: This was a …

Sepsis is the leading cause of death in critically ill patients in the United States. Yet the
individual host response to septicemia is variable, depending on the patient's immune …

Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Sepsis remains the leading cause of death in most intensive care units. Advances in
understanding the immune response to sepsis provide the opportunity to develop more …

The goal of this study was to conduct a systematic review of the literature on the relationship
between peripheral blood platelet to lymphocyte ratio (PLR) and mortality in sepsis and to …

Millions of COVID-19 patients have succumbed to respiratory and systemic inflammation.
Hyperstimulation of toll-like receptor (TLR) signaling is a key driver of immunopathology …

This mini-review emphasizes a psychoneuroimmunology (PNI) perspective of the
hypothesis that stress and surgical excision of the primary tumor can promote tumor …

A pilot study of coupled plasma filtration with adsorption i... : Critical Care Medicine A pilot study
of coupled plasma filtration with adsorption in septic shock* : Critical Care Medicine SCCM …