Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

SS Guo, ZG Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since
ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an …

T cell effects and mechanisms in immunotherapy of head and neck tumors

Y Xiang, M Gong, Y Deng, H Wang, D Ye - Cell Communication and …, 2023 - Springer
Head and neck tumors (HNCs) are a common tumor in otorhinolaryngology head and neck
surgery, accounting for 5% of all malignant tumors in the body and are the sixth most …

In vitro experimental study on the formation of microRNA-34a loaded exosomes and their inhibitory effect in oral squamous cell carcinoma

W Deng, Y Meng, B Wang, CX Wang, CX Hou, QH Zhu… - Cell Cycle, 2022 - Taylor & Francis
Studies have shown the inhibitory effect of microRNA-34a on proliferation, migration, and
invasion of oral squamous cell carcinoma. However, the lack of a safe and effective delivery …

A predictive model of immune infiltration and prognosis of head and neck squamous cell carcinoma based on cell adhesion-related genes: including molecular …

Y Liu, Z Wu, Z Fu, Y Han, J Wang, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Focal adhesion serves as a bridge between tumour cells and the extracellular
matrix (ECM) and has multiple roles in tumour invasion, migration, and therapeutic …

Characterization of macrophages in head and neck squamous cell carcinoma and development of MRG-based risk signature

L Liu, Q Liu - Scientific Reports, 2024 - nature.com
Macrophages are immune cells in the TME that can not only inhibit angiogenesis,
extracellular matrix remodeling, cancer cell proliferation, and metastasis but also mediate …

Translational research in head and neck cancer: Molecular and immunological updates

T Kumai, H Shinomiya, H Shibata, H Takahashi… - Auris Nasus …, 2024 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) has a poor prognosis. Each year,
approximately 880,000 patients are newly diagnosed with HNSCC worldwide, and 450,000 …

The association between body mass index and efficacy of pembrolizumab as second‐line therapy in patients with recurrent/metastatic head and neck squamous cell …

X Zhang, M Rui, C Lin, Z Li, D Wei, R Han… - Cancer …, 2023 - Wiley Online Library
Background Recent evidence suggested a potential correlation between BMI and the
efficacy of immune checkpoint inhibitors in cancer patients. This study aimed to evaluate the …

Evaluation of programmed death ligand 1 expression in cytology to determine eligibility for immune checkpoint inhibitor therapy in patients with head and neck …

Z Liu, M Williams, J Stewart, BS Glisson… - Cancer …, 2022 - Wiley Online Library
Background Immune checkpoint inhibitors targeting the programmed cell death protein 1
(PD‐1)/programmed cell death ligand 1 (PD‐L1) pathway have recently emerged as a …

Immune cells in head-and-neck tumor microenvironments

E Jumaniyazova, A Lokhonina, D Dzhalilova… - Journal of Personalized …, 2022 - mdpi.com
Head-and-neck cancers constitute a heterogeneous group of aggressive tumors with high
incidence and low survival rates, collectively being the sixth most prevalent cancer type …

FBXW7 promotes autophagy and inhibits proliferation of oral squamous cell carcinoma

B Qiu, Y Sun, W Nie, Q Yang… - … Inflammation and Disease, 2023 - Wiley Online Library
Background F‐box and WD repeat domain containing 7 (FBXW7) is a critical tumor
suppressor. The expression of FBXW7 is decreased in oral squamous cell carcinoma …