Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

Stroke is the leading cause of death and neurological disorders worldwide. However,
diagnostic techniques and treatments for stroke patients are still limited for certain types of …

Introduction Neuroinflammation is associated with the elevation of toxic proinflammatory
mediators that promote neurodegeneration and subsequently affect cognition. Causes of …

Ulcerative colitis (UC) is a serious inflammatory disease of the colon. The pathogenic
mechanisms of UC involve the activation of inflammatory and oxidative stress responses in …

Ischemic stroke is the most common cause of adult disability and one of the leading causes
of death worldwide, with a serious socio-economic impact. In the present work, we used a …

Introduction: Cognitive impairment is a common complication and comorbidity of diabetes.
However, the underlying mechanisms of diabetes-associated cognitive dysfunction are …

Abstract SHPL-49 ((2R, 3S, 4S, 5R, 6R)-2-(hydroxymethyl)-6-(4-(4-methoxyphenyl) butoxy)
tetrahydro-2H-pyran-3, 4, 5-triol) is a novel glycoside derivative obtained from structural …

Ischemic stroke is one of the leading causes of death and disability globally, but its treatment
options are limited due to therapeutic window and reperfusion injury constraints. Microglia …

Abstract Ethnopharmacological relevance Huanglian Jiedu Decoction (HLJDD) is a
traditional heat-dissipating and detoxicating prescription used in Chinese medicine and has …

Objective One of the newest antiseizure medication is levetiracetam (LEV). It might be
effective in various indications, not only related to convulsions. Central nervous system …