Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …

Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …

The Buthidae family of scorpions consists of arthropods with significant medical relevance,
as their venom contains a diverse range of biomolecules, including neurotoxins that …

The voltage-gated potassium channel KV 1.3 is a well-established therapeutic target for a
range of autoimmune diseases, in addition to being the site of action of many venom-derived …

Scorpionism is a relevant medical condition in Brazil. It is responsible for most accidents
involving venomous animals in the country, which leads to severe symptoms that can evolve …

Abstract The KV1. 3 voltage‐gated potassium ion channel is involved in many physiological
processes both at the plasma membrane and in the mitochondria, chiefly in the immune and …

Evolution and natural selection have endowed animal venoms, including scorpion venoms,
with a wide range of pharmacological properties. Consequently, scorpions, their venoms …

Animal venom is an important evolutionary innovation in nature. As one of the most
representative animal venoms, scorpion venom contains an extremely diverse set of …

Abstract Kv1. 3 K+ channels play a central role in the regulation of T cell activation and Ca
2+ signaling under physiological and pathophysiological conditions. Peptide toxins targeting …

T cells have a central role in systemic lupus erythematosus (SLE) pathogenesis. T-cell
dysregulation affects peripheral tolerance and induces inappropriate activation of B cells. 1 …