Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management

G Fernandez de Grado, L Keller… - Journal of tissue …, 2018 - journals.sagepub.com
Bone replacement might have been practiced for centuries with various materials of natural
origin, but had rarely met success until the late 19th century. Nowadays, many different bone …

Challenges and tissue engineering strategies of periodontal-guided tissue regeneration

Y Liu, L Guo, X Li, S Liu, J Du, J Xu, J Hu… - Tissue Engineering Part …, 2022 - liebertpub.com
Periodontitis is a chronic infectious oral disease with a high prevalence rate in the world,
and is a major cause of tooth loss. Nowadays, people have realized that the local …

[HTML][HTML] A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration

P Guo, X Liu, P Zhang, Z He, Z Li, M Alini… - Bioactive Materials, 2022 - Elsevier
The osteogenic microenvironment of bone-repairing materials plays a key role in
accelerating bone regeneration but remains incompletely defined, which significantly limits …

Silk Fibroin microparticle scaffold for use in bone void filling: safety and efficacy studies

R Deshpande, S Shukla, A Kale… - ACS Biomaterials …, 2022 - ACS Publications
Silk fibroin (SF) is a natural biocompatible protein polymer extracted from cocoons of
silkworm Bombyx mori. SF can be processed into a variety of different forms and shapes that …

Synergistic use of biomaterials and licensed therapeutics to manipulate bone remodelling and promote non-union fracture repair

CR Simpson, HM Kelly, CM Murphy - Advanced Drug Delivery Reviews, 2020 - Elsevier
Disrupted bone metabolism can lead to delayed fracture healing or non-union, often
requiring intervention to correct. Although the current clinical gold standard bone graft …

Strontium-substituted calcium sulfate hemihydrate/hydroxyapatite scaffold enhances bone regeneration by recruiting bone mesenchymal stromal cells

H Chang, H Xiang, Z Yao, S Yang… - Journal of …, 2020 - journals.sagepub.com
Fabrication of osteoconductive scaffold with osteoinductive capability and appropriate
resorption rate is of great significance for treating bone defects. To achieve this aim …

Silk fibroin and ceramic scaffolds: Comparative in vitro studies for bone regeneration

R Deshpande, S Shukla, R Sayyad… - Bioengineering & …, 2021 - Wiley Online Library
Synthetic bone void fillers based on calcium ceramics are used to fill cavities in the bone
and promote bone regeneration. More recently, silk fibroin (SF), a protein polymer obtained …

Composite bone graft of CaO–MgO–SiO 2 glass–ceramics and CaSO 4 ceramics for boosting bone formation rate

GY Hung, CY Wang, HY Hsiao, CS Tu… - Journal of Materials …, 2024 - pubs.rsc.org
This study develops a composite bone graft of CaO–MgO–SiO2 glass–ceramic and CaSO4
[abbreviated as (CMS) 3− x (CS) x] via the sponge replication technique with weight …

Cerium-containing α-calcium sulfate hemihydrate bone substitute promotes osteogenesis

H Xiang, Y Wang, H Chang, S Yang… - Journal of …, 2019 - journals.sagepub.com
Bone substitute offers a promising strategy for the reconstruction of large bone defects. It
may be feasible to develop a better substitute material by enhancing the osteoinductivity and …

Additively manufactured bioceramic scaffolds based on triply periodic minimal surfaces for bone regeneration

H Zhu, J Wang, S Wang, Y Yang… - Journal of Tissue …, 2024 - journals.sagepub.com
The study focused on the effects of a triply periodic minimal surface (TPMS) scaffolds,
varying in porosity, on the repair of mandibular defects in New Zealand white rabbits. Four …