T-type channels are low-voltage-activated calcium channels that contribute to a variety of
cellular and physiological functions, including neuronal excitability, hormone and …

Voltage-gated calcium channels are important mediators of calcium influx into electrically
excitable cells. The amount of calcium entering through this family of channel proteins is not …

Trigeminal neuralgia (TN) is a rare but debilitating disorder characterized by excruciating
facial pain, with a higher incidence in women. Recent studies demonstrated that TN patients …

T-type calcium channels represent a key pathway for Ca 2+ entry near the resting
membrane potential. Increasing evidence supports a unique role of these channels in fast …

Voltage-gated T-type Ca2+ (CaV3) channels regulate diverse physiological events,
including neuronal excitability, and have been linked to several pathological conditions such …

Key points Mutations in the Cav3. 2 T‐type Ca2+ channel were found in patients with
idiopathic generalized epilepsies, yet the mechanisms by which these mutations increase …

T-type calcium channels (T-channels) contribute to a wide variety of physiological functions,
especially in the cardiovascular and nervous systems. Recent studies using knock-out …

Trigeminal neuralgia is a rare and debilitating disorder that affects one or more branches of
the trigeminal nerve, leading to severe pain attacks and a poor quality of life. It has been …

Voltage-gated calcium channels (VGCCs) represent a key link between electrical signals
and non-electrical processes, such as contraction, secretion and transcription. Evolved to …

Neuronal voltage-gated calcium channels (VGCCs) serve complex yet essential
physiological functions via their pivotal role in translating electrical signals into intracellular …