Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

How can nanotechnology help to combat COVID-19? Opportunities and urgent need

EVR Campos, AES Pereira, JL De Oliveira… - Journal of …, 2020 - Springer
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The
most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread …

An overview of functional nanoparticles as novel emerging antiviral therapeutic agents

L Chen, J Liang - Materials Science and Engineering: C, 2020 - Elsevier
Research on highly effective antiviral drugs is essential for preventing the spread of
infections and reducing losses. Recently, many functional nanoparticles have been shown …

Nanoparticle-based vaccines against respiratory viruses

S Al-Halifa, L Gauthier, D Arpin, S Bourgault… - Frontiers in …, 2019 - frontiersin.org
The respiratory mucosa is the primary portal of entry for numerous viruses such as the
respiratory syncytial virus, the influenza virus and the parainfluenza virus. These pathogens …

Nanoparticle-mediated cancer cell therapy: Basic science to clinical applications

J Verma, C Warsame, RK Seenivasagam… - Cancer and Metastasis …, 2023 - Springer
Every sixth person in the world dies due to cancer, making it the second leading severe
cause of death after cardiovascular diseases. According to WHO, cancer claimed nearly 10 …

Classical dynamical density functional theory: from fundamentals to applications

M te Vrugt, H Löwen, R Wittkowski - Advances in Physics, 2020 - Taylor & Francis
Classical dynamical density functional theory (DDFT) is one of the cornerstones of modern
statistical mechanics. It is an extension of the highly successful method of classical density …

Mechanistic understanding from molecular dynamics simulation in pharmaceutical research 1: drug delivery

A Bunker, T Róg - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …

[HTML][HTML] A quantitative view on multivalent nanomedicine targeting

L Woythe, NB Tito, L Albertazzi - Advanced drug delivery reviews, 2021 - Elsevier
Although the concept of selective delivery has been postulated over 100 years ago, no
targeted nanomedicine has been clinically approved so far. Nanoparticles modified with …

In silico modelling of cancer nanomedicine, across scales and transport barriers

NR Stillman, M Kovacevic, I Balaz… - NPJ Computational …, 2020 - nature.com
Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …

A microfluidic platform for the controlled synthesis of architecturally complex liquid crystalline nanoparticles

CP Pilkington, C Contini, JD Barritt, PA Simpson… - Scientific Reports, 2023 - nature.com
Soft-matter nanoparticles are of great interest for their applications in biotechnology,
therapeutic delivery, and in vivo imaging. Underpinning this is their biocompatibility …