Cell genetics, culture conditions and the recovery efficiency of cells and products are the
bottlenecks for industrial bioprocesses from microalgae. Microalgae lipids can be used for …

The conversion of 7-dehydrocholesterol to cholesterol, the final step of cholesterol synthesis
in the Kandutsch-Russell pathway, is catalyzed by the enzyme 7-dehydrocholesterol …

The synthesis of cholesterol requires more than 20 enzymes, many of which are intricately
regulated. Post-translational control of these enzymes provides a rapid means for modifying …

Cholesterol biosynthesis is a highly regulated pathway, with over 20 enzymes controlled at
the transcriptional and posttranslational levels. While some enzymes remain stable …

Cholesterol synthesis is both energy-and oxygen-intensive, yet relatively little is known of
the regulatory effects of hypoxia on pathway enzymes. We previously showed that the rate …

The endoplasmic reticulum (ER) is the main center for the synthesis of various lipid types in
cells, and newly synthesized lipids are delivered from the ER to other organelles. In the past …

Epoxide functional group is a part of several natural as well as synthetic compounds.
Irrespective of the role of epoxide group in drug efficacy and the use of epoxide compounds …

Previous work from us and others has suggested that cholesterol is an important lipid in the
context of the organization of the actin cytoskeleton. However, reorganization of the actin …

With COVID-19 becoming endemic, there is a continuing need to find biomarkers
characterizing the disease and aiding in patient stratification. We studied the relation …

Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before
returning to spawn in freshwater. The transition to marine habitats is associated with …