RNA granules: functional compartments or incidental condensates?
RNA granules are mesoscale assemblies that form in the absence of limiting membranes.
RNA granules contain factors for RNA biogenesis and turnover and are often assumed to …
RNA granules contain factors for RNA biogenesis and turnover and are often assumed to …
Conformational ensembles of the human intrinsically disordered proteome
Intrinsically disordered proteins and regions (collectively, IDRs) are pervasive across
proteomes in all kingdoms of life, help to shape biological functions and are involved in …
proteomes in all kingdoms of life, help to shape biological functions and are involved in …
MolPhase, an advanced prediction algorithm for protein phase separation
Q Liang, N Peng, Y Xie, N Kumar, W Gao… - The EMBO …, 2024 - embopress.org
We introduce MolPhase, an advanced algorithm for predicting protein phase separation
(PS) behavior that improves accuracy and reliability by utilizing diverse physicochemical …
(PS) behavior that improves accuracy and reliability by utilizing diverse physicochemical …
Aggregation of the Amyloid-beta Peptide (Abeta40) within Condensates Generated through Liquid-Liquid Phase Separation
The deposition of the Abeta peptide into amyloid fibrils is characteristic of Alzheimer's
disease. As it has been recently observed that the process of amyloid aggregation can take …
disease. As it has been recently observed that the process of amyloid aggregation can take …
[HTML][HTML] Potential Benefits of Crowd-Collaborative Farming in Sustaining Small Scale Dairy Farming Business Performance
MO Penwell, NT Sam, R Tshepo… - International …, 2023 - journals.researchsynergypress.com
Protein codes promote selective subcellular compartmentalization
HR Kilgore, I Chinn, PG Mikhael, I Mitnikov… - bioRxiv, 2024 - biorxiv.org
Cells have evolved mechanisms to distribute~ 10 billion protein molecules to subcellular
compartments where diverse proteins involved in shared functions must efficiently …
compartments where diverse proteins involved in shared functions must efficiently …
[HTML][HTML] Glycogen phase separation drives macromolecular rearrangement and asymmetric division in E. coli
Y Thappeta, SJ Canas-Duarte, T Kallem, A Fragasso… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Bacteria often experience nutrient limitation in nature and the laboratory. While exponential
and stationary growth phases are well characterized in the model bacterium Escherichia …
and stationary growth phases are well characterized in the model bacterium Escherichia …
Preserving condensate structure and composition by lowering sequence complexity
Biomolecular condensates play a vital role in organizing cellular chemistry. They selectively
partition biomolecules, preventing unwanted cross-talk and buffering against chemical …
partition biomolecules, preventing unwanted cross-talk and buffering against chemical …
PICNIC identifies condensate-forming proteins across organisms
Biomolecular condensates are membrane-less organelles that selectively concentrate
biomolecules to perform a multitude of fundamental biochemical functions. Despite their …
biomolecules to perform a multitude of fundamental biochemical functions. Despite their …
Chemical codes promote selective compartmentalization of proteins.
HR Kilgore, I Chinn, PG Mikhael, I Mitnikov… - Biorxiv: the Preprint …, 2024 - europepmc.org
Cells have evolved mechanisms to distribute~ 10 billion protein molecules to subcellular
compartments where diverse proteins involved in shared functions must efficiently …
compartments where diverse proteins involved in shared functions must efficiently …