A first computational frame for recognizing heparin-binding protein

W Zhu, SS Yuan, J Li, CB Huang, H Lin, B Liao - Diagnostics, 2023 - mdpi.com
Heparin-binding protein (HBP) is a cationic antibacterial protein derived from multinuclear
neutrophils and an important biomarker of infectious diseases. The correct identification of …

Machine learning approaches in diagnosis, prognosis and treatment selection of cardiac amyloidosis

A Allegra, G Mirabile, A Tonacci, S Genovese… - International Journal of …, 2023 - mdpi.com
Cardiac amyloidosis is an uncommon restrictive cardiomyopathy featuring an unregulated
amyloid protein deposition that impairs organic function. Early cardiac amyloidosis …

Bitter-RF: a random forest machine model for recognizing bitter peptides

YF Zhang, YH Wang, ZF Gu, XR Pan, J Li… - Frontiers in …, 2023 - frontiersin.org
Introduction Bitter peptides are short peptides with potential medical applications. The huge
potential behind its bitter taste remains to be tapped. To better explore the value of bitter …

A systematic review on the state-of-the-art strategies for protein representation

ZX Yue, TC Yan, HQ Xu, YH Liu, YF Hong… - Computers in Biology …, 2023 - Elsevier
The study of drug-target protein interaction is a key step in drug research. In recent years,
machine learning techniques have become attractive for research, including drug research …

Prediction of amyloid proteins using embedded evolutionary & ensemble feature selection based descriptors with eXtreme gradient boosting model

S Akbar, H Ali, A Ahmad, MR Sarker, A Saeed… - IEEE …, 2023 - ieeexplore.ieee.org
Amyloid proteins (AMYs) are usually an aggregate of insoluble fibrous that have major
pathogenic effects on various tissues. However, its abnormal deposition may lead to several …

Identification of adaptor proteins using the ANOVA feature selection technique

YH Wang, YF Zhang, Y Zhang, ZF Gu, ZY Zhang, H Lin… - Methods, 2022 - Elsevier
The adaptor proteins play a crucially important role in regulating lymphocyte activation.
Rapid and efficient identification of adaptor proteins is essential for understanding their …

[HTML][HTML] IBPred: A sequence-based predictor for identifying ion binding protein in phage

SS Yuan, D Gao, XQ Xie, CY Ma, W Su… - Computational and …, 2022 - Elsevier
Ion binding proteins (IBPs) can selectively and non-covalently interact with ions. IBPs in
phages also play an important role in biological processes. Therefore, accurate identification …

ENTAIL: yEt aNoTher amyloid fIbrils cLassifier

A Auriemma Citarella, L Di Biasi, F De Marco… - BMC …, 2022 - Springer
Background This research aims to increase our knowledge of amyloidoses. These disorders
cause incorrect protein folding, affecting protein functionality (on structure). Fibrillar deposits …

[HTML][HTML] Multi-headed Ensemble Residual CNN: A Powerful Tool for Fibroblast Growth Factor Prediction

N Almusallam, F Ali, H Kumar, T Alkhalifah… - Results in …, 2024 - Elsevier
Abstract Fibroblast Growth Factor (FGF) performs a significant role in the repair, nervous
system, development, and maintenance, making it a promising target for treating …

AAclust: k-optimized clustering for selecting redundancy-reduced sets of amino acid scales

S Breimann, D Frishman - Bioinformatics Advances, 2024 - academic.oup.com
Amino acid scales are crucial for sequence-based protein prediction tasks, yet no gold
standard scale set or simple scale selection methods exist. We developed AAclust, a …