Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …

The tightly orchestrated temporal and spatial control of signal transducer and activator of
transcription 3 (STAT3) activity in epithelial, immune and stromal cells is critical for wound …

Age is a non-modifiable risk factor for the inflammation that underlies age-associated
diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine …

Huntington's disease (HD) is an inherited neurodegenerative disorder with adult-onset
clinical symptoms, but the mechanism by which aging drives the onset of neurodegeneration …

Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

Autophagy is a cellular survival mechanism that is induced by cancer therapy, among other
stresses, and frequently contributes to cancer cell survival during long periods of dormancy …

Extracellular cytokines are enriched in the tumor microenvironment and regulate various
important properties of cancers, including autophagy. However, the precise molecular …

The role of circular RNA in cancer is emerging. A newly reported circular RNA HIPK3
(circHIPK3) is critical in cell proliferation of various cancer types, although its role in non …

Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …

Abstract Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor
with many important functions in the biology of normal and transformed cells. Its regulation is …